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Search term: 3T3-L1 cell

Results 1 - 88 of 88
EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase 3T3-L1 cell - 686411, 697625, 700121, 700180, 712594, 740806
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase 3T3-L1 cell differentiation of cells causes a strong increase in 11beta-hydroxysteroid dehydrogenase protein levels, occuring late in the differentiation protocol. Reduction of 11beta-hydroxysteroid dehydrogenase activity in 3T3-L1 fibroblasts, achieved by pharmacological inhibition or adenovirally mediated delivery of short hairpin RNA constructs, specifically blocks the ability of inactive glucocorticoids to drive 3T3-L1 differentiation. Even modest increases in exogenous 11beta-hydroxysteroid dehydrogenase expression in 3T3-L1 fibroblasts, to levels comparable with endogenous 1 11beta-hydroxysteroid dehydrogenase in differentiated 3T3-L1 adipocytes, are sufficient to block adipogenesis 692987
Show all pathways known for 1.1.1.188Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.188prostaglandin-F synthase 3T3-L1 cell AKR1B3 mRNA 9 is expressed in preadipocytes, and its level increases about 4fold at day 1 after initiation of adipocyte differentiation, and then quickly decreases the following day to a level lower than that in the preadipocytes 712494
Show all pathways known for 1.1.1.205Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.205IMP dehydrogenase 3T3-L1 cell - 702061
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) 3T3-L1 cell - 739138
Show all pathways known for 1.1.1.44Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.44phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) 3T3-L1 cell - 685541
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.8glycerol-3-phosphate dehydrogenase (NAD+) 3T3-L1 cell - 699948, 760740
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20prostamide/prostaglandin F2alpha synthase 3T3-L1 cell - 740711
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.4procollagen-lysine 5-dioxygenase 3T3-L1 cell - 745769
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.66[histone H3]-trimethyl-L-lysine9 demethylase 3T3-L1 cell - 746217
Display the word mapDisplay the reaction diagram Show all sequences 1.14.18.64-hydroxysphinganine ceramide fatty acyl 2-hydroxylase 3T3-L1 cell - 734433
Show all pathways known for 1.14.19.1Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.1stearoyl-CoA 9-desaturase 3T3-L1 cell - 687766, 746212
Show all pathways known for 1.14.19.1Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.1stearoyl-CoA 9-desaturase 3T3-L1 cell conjugated linoleic acid decreases SCD1 gene expression 675626
Show all pathways known for 1.14.19.1Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.1stearoyl-CoA 9-desaturase 3T3-L1 cell isozyme SCD1 is dramatically induced during 3T3L1 differentiation 746542
Show all pathways known for 1.17.1.4Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.4xanthine dehydrogenase 3T3-L1 cell mRNA expression increases 8-fold during the first 12 hr postinduction and subsequently declines to preinduction levels by day 3. Xanthine dehydrogenase activity is maximally induced at 24 hr postinduction, while xanthine oxidase activity remains relatively unchanged 672979
Display the word mapDisplay the reaction diagram Show all sequences 1.2.3.1aldehyde oxidase 3T3-L1 cell preadipocytes have a very low expression of AOX1, in 2 days differentiated cells AOX1 is induced and is not further upregulated in 3, 7 and 9 days differentiated cells. AOX1 mRNA is nearly four-fold higher in 2 days differentiated cells when compared to preadipocytes and doubles from days 2 to 6 697933
Show all pathways known for 1.3.1.48Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.4813,14-dehydro-15-oxoprostaglandin 13-reductase 3T3-L1 cell - 687562
Show all pathways known for 1.3.3.6Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.6acyl-CoA oxidase 3T3-L1 cell - 671758
Display the word mapDisplay the reaction diagram Show all sequences 1.3.99.23all-trans-retinol 13,14-reductase 3T3-L1 cell - -, 700994, 763507
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) 3T3-L1 cell - 685345
Display the reaction diagram Show all sequences 2.1.1.1nicotinamide N-methyltransferase 3T3-L1 cell elevated enzyme activity during cell differentiation in adipose tissue 701990
Show all pathways known for 2.1.1.17Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.17phosphatidylethanolamine N-methyltransferase 3T3-L1 cell - 719858
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.348mRNA m6A methyltransferase 3T3-L1 cell - 757661
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.108alpha-tubulin N-acetyltransferase 3T3-L1 cell - 735631
Show all pathways known for 2.3.1.15Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.15glycerol-3-phosphate 1-O-acyltransferase 3T3-L1 cell - 756106, 757868
Show all pathways known for 2.3.1.15Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.15glycerol-3-phosphate 1-O-acyltransferase 3T3-L1 cell Gpat3 mRNA increases 60fold during differentiation of 3T3-L1 preadipocytes to mature adipocytes, suggesting a critical role in adipocytes 701623
Show all pathways known for 2.3.1.15Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.15glycerol-3-phosphate 1-O-acyltransferase 3T3-L1 cell pre- and post-adipocytes 688948
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.20diacylglycerol O-acyltransferase 3T3-L1 cell - 758179
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.20diacylglycerol O-acyltransferase 3T3-L1 cell 3T3-L1 fibroblasts differentiated into adipocytes 486513
Show all pathways known for 2.3.1.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.21carnitine O-palmitoyltransferase 3T3-L1 cell CPT I and CPT II 486577
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.48histone acetyltransferase 3T3-L1 cell - 688978
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.85fatty-acid synthase system 3T3-L1 cell - 660895
Show all pathways known for 2.3.3.8Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.8ATP citrate synthase 3T3-L1 cell - 736797
Show all pathways known for 2.4.1.11Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.11glycogen(starch) synthase 3T3-L1 cell synthetic peroxisome proliferator-activated receptor beta/delta, and gamma agonists markedly up-regulate Gys-2 mRNA and protein expression in mouse 3T3-L1 adipocytes 686019
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.255protein O-GlcNAc transferase 3T3-L1 cell - 693100
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.80ceramide glucosyltransferase 3T3-L1 cell - 679436
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide phosphoribosyltransferase 3T3-L1 cell - 735872, 759503
Display the reaction diagram Show all sequences 2.4.3.1beta-galactoside alpha-(2,6)-sialyltransferase 3T3-L1 cell - 759485
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.137phosphatidylinositol 3-kinase 3T3-L1 cell - 709772
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1501-phosphatidylinositol-3-phosphate 5-kinase 3T3-L1 cell - 723139
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154phosphatidylinositol-4-phosphate 3-kinase 3T3-L1 cell adipocyte 640921
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.671-phosphatidylinositol 4-kinase 3T3-L1 cell - 676001
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.1receptor protein-tyrosine kinase 3T3-L1 cell - 721490
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.1receptor protein-tyrosine kinase 3T3-L1 cell HER2 is absent in undifferentiated cultures of adipocytes, not subjected to hormonal treatment but processed at the same time as the differentiating cultures from day 0 to day 14. Expression of HER2 significantly augments during the differentiation of preadipocytes. HER2 acculmulation reaches a maximum at day 9 693316
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.1non-specific serine/threonine protein kinase 3T3-L1 cell - 761503
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.1non-specific serine/threonine protein kinase 3T3-L1 cell isozyme PKNalpha 662053
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.11cAMP-dependent protein kinase 3T3-L1 cell - 694155
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.24mitogen-activated protein kinase 3T3-L1 cell - 740424
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.31[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase 3T3-L1 cell - 665636, 702510, 703277
Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.21inositol-hexakisphosphate 5-kinase 3T3-L1 cell - 738392
Show all pathways known for 2.7.4.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.3adenylate kinase 3T3-L1 cell - 722732
Show all pathways known for 2.7.7.41Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.41phosphatidate cytidylyltransferase 3T3-L1 cell - 738826
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.4estrone sulfotransferase 3T3-L1 cell - -, 725979, 760988
Show all pathways known for 3.1.1.3Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.3triacylglycerol lipase 3T3-L1 cell - 707547, 708289
Show all pathways known for 3.1.1.3Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.3triacylglycerol lipase 3T3-L1 cell adipocytes, enzyme expression during differentiation of adipocytes, maximal at day 8, overview 664719
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.34lipoprotein lipase 3T3-L1 cell preadipocyte cell line -, 709009
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.34lipoprotein lipase 3T3-L1 cell scopoletin significantly increases lipoprotein lipase activity in 3T3-L1 adipocytes 680239
Show all pathways known for 3.1.1.5Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.5lysophospholipase 3T3-L1 cell - 693213
Show all pathways known for 3.1.1.79Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.79hormone-sensitive lipase 3T3-L1 cell - 714794
Show all pathways known for 3.1.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.1alkaline phosphatase 3T3-L1 cell activity increases during adipogenesis 677519
Show all pathways known for 3.1.3.4Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.4phosphatidate phosphatase 3T3-L1 cell - 680814, 708998, 709417, 709945, 714316
Show all pathways known for 3.1.3.4Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.4phosphatidate phosphatase 3T3-L1 cell lipin-1 and lipin-2 707555
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.46fructose-2,6-bisphosphate 2-phosphatase 3T3-L1 cell - 751121
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.46fructose-2,6-bisphosphate 2-phosphatase 3T3-L1 cell adipocyte cell line 664718
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.48protein-tyrosine-phosphatase 3T3-L1 cell - 729290
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.86phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 3T3-L1 cell - 750315
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.11phosphoinositide phospholipase C 3T3-L1 cell - 716113
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.3cystinyl aminopeptidase 3T3-L1 cell - -, 669191, 683133, 709666, 754109, 755404
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.4tripeptide aminopeptidase 3T3-L1 cell - 679509
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46complement factor D 3T3-L1 cell - 755129
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B26proprotein convertase 5 3T3-L1 cell - 675967
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.38cathepsin K 3T3-L1 cell - 695943
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.38cathepsin K 3T3-L1 cell ATCC CL-173 697619
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.52calpain-1 3T3-L1 cell - 707364
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B3matrix metalloproteinase-11 3T3-L1 cell - 694496
Show all pathways known for 3.5.4.16Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.16GTP cyclohydrolase I 3T3-L1 cell adipocyte cell line 667769
Display the word mapDisplay the reaction diagram Show all sequences 3.6.5.2small monomeric GTPase 3T3-L1 cell - 699992, 701352
Show all pathways known for 4.1.1.29Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.29sulfinoalanine decarboxylase 3T3-L1 cell - 693792
Show all pathways known for 4.1.1.65Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.65phosphatidylserine decarboxylase 3T3-L1 cell - 715603
Show all pathways known for 4.1.2.27Display the word mapDisplay the reaction diagram Show all sequences 4.1.2.27sphinganine-1-phosphate aldolase 3T3-L1 cell - 681269
Show all pathways known for 4.1.2.27Display the word mapDisplay the reaction diagram Show all sequences 4.1.2.27sphinganine-1-phosphate aldolase 3T3-L1 cell CL 173 (ATCC) 5119
Display the word mapDisplay the reaction diagram Show all sequences 5.2.1.8peptidylprolyl isomerase 3T3-L1 cell - 715609
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2DNA topoisomerase (ATP-hydrolysing) 3T3-L1 cell - 747492
Show all pathways known for 6.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.1acetate-CoA ligase 3T3-L1 cell marked induction of AceCS1 mRNA and protein during differentiation of 3T3-L1 cells, neither AceCS2 mRNA nor protein is detected in undifferentiated or differentiated 3T3-L1 cells 652101
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.16acetoacetate-CoA ligase 3T3-L1 cell - 691065, 727116
Show all pathways known for 6.2.1.3Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.3long-chain-fatty-acid-CoA ligase 3T3-L1 cell - 662593
Show all pathways known for 6.3.4.2Display the word mapDisplay the reaction diagram Show all sequences 6.3.4.2CTP synthase (glutamine hydrolysing) 3T3-L1 cell - 727427
Show all pathways known for 6.4.1.1Display the word mapDisplay the reaction diagram Show all sequences 6.4.1.1pyruvate carboxylase 3T3-L1 cell - 690828, 705517
Results 1 - 88 of 88