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EC Number	kcat/KM Value [1/mMs^-1]	kcat/KM Value Maximum [1/mMs^-1]	Substrate	Commentary	Reference
2.4.2.8	0.0003	-	diphosphate	mutant E196D	705998
2.4.2.8	0.002	-	diphosphate	wild-type enzyme	705998
2.4.2.8	0.0024	-	IMP	mutant E196D	705998
2.4.2.8	0.004	-	5-phospho-alpha-D-ribose 1-diphosphate	mutant E196R	705998
2.4.2.8	0.0049	-	hypoxanthine	pH 7.4, 25°C	759072
2.4.2.8	0.016	-	IMP	wild-type enzyme	705998
2.4.2.8	0.02	-	5-phospho-alpha-D-ribose 1-diphosphate	mutant E196A	705998
2.4.2.8	0.027	-	6-fluoro-3-hydroxy-2-pyrazinecarboxamide	at pH 7.4 and 37°C	736838
2.4.2.8	0.034	-	IMP	mutant E196Q	705998
2.4.2.8	0.036	-	5-phospho-alpha-D-ribose 1-diphosphate	pH 7.4, 37°C, recombinant nonactivated mutant W181Y	760104

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Release 2023.1 (January 2023)