Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search General Information

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 30 > >>
download as CSV
download all results as CSV
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction causal role of the elevated symmetric methylation of H3R8 and H4R3 at the RBL2 promoter in transformed B-lymphocyte pathology 688977
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction isoform PRMT2 silencing can enhance 17beta-estradiol-induced proliferation by regulating E2F1 expression and E2F1-responsive genes in estrogen receptor alpha-positive breast cancer cells 719469
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction isoform PRMT7 knockdown causes a significant decrease in enzyme recruitment and hsitone H2A-arginine 3/histone H4-arginine 3 methylation 720039
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction knockdown of PRMT6 disrupts oestrogen-stimulated transcription of endogenous GREB1 and progesterone receptor in MCF-7 breast cancer cells. Knockdown of PRMT6 increases the exon inclusion:skipping ratio of alternatively spliced exons in endogenous vascular endothelial growth factor and spleen tyrosine kinase RNA transcripts in both the presence and absence of oestrogen 720581
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction mutations of protein arginine methyltransferase 10 result in a late-flowering phenotype 720960
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction PRMT5 deficiency is associated with late flowering. Mutation of PRMT5 leads to widespread splicing defects 720902
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125malfunction silencing PRMT5 expression strongly inhibits proliferation of lung adenocarcinoma cells 718797
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125physiological function CARM1 functions as a rather general transcriptional coactivator, much like p300/CBP. A possible scaffolding role for CARM1, that is a component of the nucleosomal methylation activator complex 704652
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125physiological function CARM1 is a dual functional coregulator that facilitates transcription initiation by methylation of Arg17 and Arg26 of histone H3 and also dictates the subsequent coactivator complex disassembly by methylation of the steroid receptor coactivator family coactivators and p300/cAMP-response element-binding protein-binding protein. CARM1 function is regulated by phosphorylation at Ser217 704604
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.125physiological function increased PRMT1 activity is associated with breast cancer (e.g., increased estrogen receptor alpha signaling) and heart disease (e.g., decreased nitric oxide production) 720433
Results 1 - 10 of 30 > >>
download as CSV
download all results as CSV