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1.11.1.8
metabolism
the enzyme catalyzes the transfer of iodine to thyroglobulin during thyroid hormone synthesis
725615
1.11.1.8
physiological function
thyroid peroxidase is the key enzyme involved in thyroid hormone synthesis
712628
1.11.1.8
physiological function
treatment of animals with inhibitors propylthiouracil or methimazole decreases thyroid hormone triiodothyronine and tetraiodothyronine levels in the thyroid gland and increases thyroid-stimulating hormone level. Less than 30% inhibition of TPO in vitro is sufficient to reduce serum tetraiodothyronine level by 20%
765858
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