EC Number   |
Expression |
Reference |
|---|
    6.3.5.4 | down |
OsAS2 mRNA content decreases in roots when NH4+ is supplied |
746041 |
| 6.3.5.4 | up |
ASNS activity is highly responsive to cellular stress, primarily by increased transcription from the single gene located on chromosome 7. The transcription factor ATF4 binds to an enhancer element within the proximal promoter of the ASNS gene and activates transcription |
745375 |
| 6.3.5.4 | up |
gene PpAS1 expression is upregulated during drought, and in the dark in all organs. PpAS1 transcripts accumulate with seedlings that are grown under high concentrations of nitrate or ammonium. Ability of PtMYB1 to activate the transcription of PpAS1 in vivo, PtMYB1 negatively regulates PpAS1 promoter in pine protoplasts |
727578 |
| 6.3.5.4 | up |
human enzyme activity is highly regulated in response to cell stress, primarily by increased transcription from a single gene located on chromosome 7. Protein limitation or an imbalanced dietary amino acid composition activate the ASNS gene through the amino acid response, a process that is replicated in cell culture through limitation for any single essential amino acid. Endoplasmic reticulum stress also increases ASNS transcription through the PERK-eIF2-ATF4 arm of the unfolded protein response. Both the amino acid response and unfolded protein response lead to increased synthesis of ATF4, which binds to the C/EBP-ATF response element and induces ASNS transcription |
726657 |
| 6.3.5.4 | up |
infection with Xanthomonas campestris pv. vesicatoria induces early and strong CaAS1 expression in leaves. Significant induction of CaAS1 expression occurs in pepper leaves following treatment with salicylic acid, methyl jasmonate or wounding |
716548 |
| 6.3.5.4 | up |
infection with Xanthomonas campestris pv. vesicatoria induces early and strong CaAS1 expression in pepper leaves |
716548 |
| 6.3.5.4 | up |
transcription factor ATF4 induces asparagine synthetase which results in glutamine-dependent asparagine synthesis from aspartate, in turn asparagine accumulation then suppresses GCN2 and reduces ATF4 |
745756 |
