EC Number   |
Expression |
Reference |
|---|
   2.4.1.102 | down |
activation-induced enzyme up-regulation under permissive (T helper type 1) conditions is strongly reduced by cyclosporin A |
722382 |
| 2.4.1.102 | down |
GCNT3 downregulation by shGCNT3 7, of several shRNAs targeting GCNT3 shGCNT3s, shGCNT3 7 has the best inhibitory capacity (protein and mRNA) |
760171 |
| 2.4.1.102 | down |
inhibitor talniflumate alone and in combination with low-dose gefitinib reduced GCNT3 expression, leading to the disrupted production of mucins in vivo and in vitro |
-, 735883 |
| 2.4.1.102 | down |
no expression in normal pancreatic tissue |
706059 |
| 2.4.1.102 | more |
STAT4 controls Gcnt1 expression in Th1 cells, several conserved and non-conserved predicted STAT4 binding sites are determined |
759781 |
| 2.4.1.102 | up |
interleukin-12 induces enzyme expression |
722382 |
| 2.4.1.102 | up |
modulation of GCNT3 expression in the presence of 5-fluorouracil (5FU) at 0.03 mM, a robust induction of GCNT3 expression is observed in SW family of non-resistant cells with a statistically significant 3.76fold increase in SW620 metastatic cells, while no such induction is observed in SW5FU cells or in HT-29 cell line, which has the highest levels of endogenous GCNT3 |
760171 |
| 2.4.1.102 | up |
the three chemotherapeutic agents, with different mechanism of action, 5-fluorouracil, bortezomib and paclitaxel significantly induce GCNT3 expression in several cancer cells, but not in drug-unreponsive cells |
736047 |
