EC Number |
Expression |
Reference |
---|
1.2.4.4 | down |
the total amount of hepatic enzyme is significantly decreased in diet-induced obesity rats |
741079 |
1.2.4.4 | down |
total BCKDC activity and protein abundance of E1alpha, E1beta, and E2 subunits are markedly lower in Otsuka Long-Evans Tokushima Fatty (OLETF) than in Long-Evans Tokushima Otsuka (LETO) rats at 8 and 25 weeks of age. In addition, hepatic BCKDC activity and protein amounts are significantly decreased in LETO rats aged 25 weeks than in LETO rats aged 8 weeks. In skeletal muscle, subunits E1beta and E2 proteins are significantly reduced in OLETF rats |
712934 |
1.2.4.4 | more |
mRNA expression is not upregulated by bezafibrate treatment |
723788 |
1.2.4.4 | up |
donor hepatocytes expressing wild type BCKDH engrafted into intermediate maple syrup urine disease recipient liver, increase liver BCKDH activity. Hepatocyte transplantation increases liver BCKDH activity 14.36% of control activity |
713078 |
1.2.4.4 | up |
in skeletal muscle, subunits E1alpha protein is significantly reduced in OLETF rats |
712934 |