EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
2.7.11.10 | 762079 |
A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase beta in colorectal cancer in vivo and in vitro |
Oncotarget |
8 |
91258-91269 |
2017 |
Homo sapiens |
29207641 |
2.7.11.10 | 761803 |
Curcumin alleviates lipopolysaccharide (LPS)-activated neuroinflammation via modulation of miR-199b-5p/IkappaB kinase beta (IKKbeta)/nuclear factor kappa B (NF-kappaB) pathway in microglia |
Med. Sci. Monit. |
25 |
9801-9810 |
2019 |
Mus musculus |
31862869 |
2.7.11.10 | 761714 |
Discovery of novel potent nuclear factor kappa-B inhibitors (IKK-beta) via extensive ligand-based modeling and virtual screening |
J. Mol. Recognit. |
30 |
e2604 |
2017 |
Homo sapiens |
28008665 |
2.7.11.10 | 761671 |
Inhibitory kappa B kinase alpha (IKKalpha) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers |
J. Med. Chem. |
60 |
7043-7066 |
2017 |
Homo sapiens |
28737909 |
2.7.11.10 | 761776 |
Involvement of inhibitor kappa B kinase 2 (IKK2) in the regulation of vascular tone |
Lab. Invest. |
98 |
1311-1319 |
2018 |
Rattus norvegicus |
29785049 |
2.7.11.10 | 761544 |
Molecular mechanism of interactions between chrysin and I-kappa-B kinase epsilon (IKKe)/tank binding kinase-1(TBK1) Cell-based assay and in silico molecular docking studies |
J. Biomol. Struct. Dyn. |
38 |
589-596 |
2020 |
Homo sapiens |
30767626 |
2.7.11.10 | 760461 |
Non-activatable mutant of inhibitor of kappa B kinase alpha (IKKalpha) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice |
Atherosclerosis |
292 |
23-30 |
2020 |
Mus musculus |
31733453 |
2.7.11.10 | 760481 |
RNF8 negatively regulates NF-kappaB signaling by targeting IkappaB kinase implications for the regulation of inflammation signaling |
Biochem. Biophys. Res. Commun. |
488 |
189-195 |
2017 |
Homo sapiens |
28499869 |
2.7.11.10 | 694114 |
17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells |
Mol. Cancer Ther. |
7 |
1523-1532 |
2008 |
Homo sapiens |
18566223 |
2.7.11.10 | 674835 |
A critical role for IkappaB kinase beta in metallothionein-1 expression and protection against arsenic toxicity |
J. Biol. Chem. |
282 |
21487-21496 |
2007 |
Mus musculus |
17526490 |