EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
2.4.2.4 | 759610 |
Design of novel inhibitors of human thymidine phosphorylase synthesis, enzyme inhibition, in vitro toxicity, and impact on human glioblastoma cancer |
J. Med. Chem. |
62 |
1231-1245 |
2019 |
Homo sapiens |
30615449 |
2.4.2.4 | 758895 |
Design, synthesis, in-vitro thymidine phosphorylase inhibition, in-vivo antiangiogenic and in-silico studies of C-6 substituted dihydropyrimidines |
Bioorg. Chem. |
80 |
99-111 |
2018 |
Escherichia coli |
29894893 |
2.4.2.4 | 760039 |
Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase |
PLoS ONE |
13 |
e0202826 |
2018 |
Homo sapiens |
30138393 |
2.4.2.4 | 758897 |
Identification of 1,2,4-triazoles as new thymidine phosphorylase inhibitors future anti-tumor drugs |
Bioorg. Chem. |
85 |
209-220 |
2019 |
Escherichia coli |
30634096 |
2.4.2.4 | 758892 |
In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase |
Bioorg. Chem. |
68 |
80-89 |
2016 |
Escherichia coli |
27474803 |
2.4.2.4 | 759039 |
Interdomain twists of human thymidine phosphorylase and its active-inactive conformations binding of 5-FU and its analogues to human thymidine phosphorylase versus dihydropyrimidine dehydrogenase |
Chem. Biol. Drug Des. |
94 |
1956-1972 |
2019 |
Homo sapiens |
31356728 |
2.4.2.4 | 759338 |
Kinetics mechanism and regulation of native human hepatic thymidine phosphorylase |
Int. J. Biochem. Cell Biol. |
110 |
122-129 |
2019 |
Homo sapiens |
30849523 |
2.4.2.4 | 759338 |
Kinetics mechanism and regulation of native human hepatic thymidine phosphorylase |
Int. J. Biochem. Cell Biol. |
110 |
122-129 |
2019 |
Mus musculus |
30849523 |
2.4.2.4 | 760047 |
Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors in vitro biochemical inhibition, mechanistic, and in silico modeling studies |
PLoS ONE |
14 |
e0225056 |
2019 |
Escherichia coli |
31743355 |
2.4.2.4 | 759143 |
Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer |
Eur. J. Med. Chem. |
124 |
992-1003 |
2016 |
Escherichia coli |
27783978 |