EC Number   |
Posttranslational Modification |
Reference |
|---|
    6.2.1.1 | acetylation |
- |
745793, 746272 |
| 6.2.1.1 | acetylation |
posttranslational regulation by acetylation of Lys609. Acetylation blocks synthesis of the adenylate intermediate but does not affect the thioester-forming activity of the enzyme |
653891 |
| 6.2.1.1 | acetylation |
the enzyme is poorly acetylated in vitro by the Streptomyces lividans protein acetyltransferase Pat |
746272 |
| 6.2.1.1 | acetylation |
the enzyme is regulated by a Sir2-dependent protein acetylation/deacetylation system. Leu641 is critical for the acetylation of the enzyme by protein acetyltransferase.Mutation at Leu641 prevents the acetylation of Acs by protein acetyltransferase and maintains the acetyl-coenzyme A synthetase in its active state |
662385 |
| 6.2.1.1 | proteolytic modification |
the putative mitochondrial targeting signal is cleaved during the transportation of the enzyme into the mitochondria matrix |
652101 |
| 6.2.1.1 | side-chain modification |
the acetyltransferase enzyme, AcuA, controls the activity of the acetyl coenzyme A synthetase, AcsA, by acetylating residue Lys549, overview |
692866 |
