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Posttranslational Modification
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1.1.99.28
proteolytic modification
GFOR is synthesized in the cytoplasm with a 52-residue signal peptide, giving a precursor form, preGFOR, that is fully active and has its cofactor tightly bound
654586
1.1.99.28
proteolytic modification
K123A mutant enzyme shows processing behavior comparable to wild-type enzyme, S116D mutant enzyme and S116D/K121A/K123Q/I124K mutant enzyme shows significantly retarded processing kinetics with residual unprocessed form being detectable even after 60 min, K121A mutant enzyme is not processed within 60 min
655405
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