EC Number   |
Application |
Reference |
|---|
   3.4.21.7 | agriculture |
effect of plasmin on in vitro embryo production. Plasmin added to the 18 h in vitro maturation medium increases the maturation rate of embryos without affecting fertilization or embryo development rates |
701162 |
| 3.4.21.7 | analysis |
electrochemical assay of plasmin activity based on a ferrocenyl peptide substrate having a plasmin-specific substrate sequence, Lys-thr-Phe-Lys, and immobilized on a gold electrode. Detection limit for plasmin is around 50 ng/ml or 0.15 mU/ml. Ratio of kcat/Km values is 0.063 microM/s |
695548 |
| 3.4.21.7 | degradation |
cleavage at Arg336 is a central mechanism of plasmin-catalyzed factor VIII inactivation. Cleavages at Arg336 and Lys36 are selectively regulated by the A2 and A3-C1-C2 domains, respectively, interacting with plasmin |
687666 |
| 3.4.21.7 | food industry |
milk retentate with increased plasmin activity is an interesting starting material for cheese-making. Increased plasmin activity increases cheese flavour and decreases ripening time |
717666 |
| 3.4.21.7 | food industry |
the enzyme is responsible for spoilage of directly heated ultra-high temperature milk products |
753817 |
| 3.4.21.7 | medicine |
11% of patients with systemic reactions to Hymenoptera stings display increased serum baseline plasmin level and 70% of these have a history of anaphylaxis. Indication of bone marrow examination for the diagnosis of clonal mast cell disease |
698446 |
| 3.4.21.7 | medicine |
16% of patients with a history of systemic reaction to Hymenoptera and Diptera venom show an elevated level of plasmin. These patients report fewer usual skin reactions, more flushing and frequently do not present skin reaction. Mastocytosis was diagnosed in 33% of patients with elevated plasmin level |
697405 |
| 3.4.21.7 | medicine |
a mutant, noninhibitory plasminogen activator inhibitor-type 1 reduces pathological ECM accumulation in anti-thy-1 nephritis, in large part through effectively competing with native plasminogen activator inhibitor-type 1, thereby restoring plasmin generation and increasing plasmin-dependent degradation of matrix components |
688737 |
| 3.4.21.7 | medicine |
a reversibly acylated plasmin-staphylokinase complex might be protected from rapid irreversible inhibition by alpha2-antiplasmin in plasma, exhibits a prolonged plasma half-life and has altered pharmacodynamic properties |
95563 |
| 3.4.21.7 | medicine |
antifibrinolytic inhibitors, e.g. aprotinin, of the serine protease plasmin are commonly used to reduce bleeding during surgery |
717259 |
