EC Number   |
Application |
Reference |
|---|
   3.4.21.107 | biotechnology |
htrA mutants show improved expression of envelope-associated proteins |
653255 |
| 3.4.21.107 | medicine |
aroC aroD HtrA mutant shows promise as a typhoid vaccine in humans |
653255 |
| 3.4.21.107 | medicine |
cigarette smokeinduced methylation of HtrA3 can contribute to the etiology of chemoresistant disease in smoking-related lung cancer |
717505 |
| 3.4.21.107 | medicine |
HtrA is an antigen for serum immunglobulin G during Chlamydia trachomatis sexually transmitted infection, but is not associated with pathology |
712876 |
| 3.4.21.107 | medicine |
HtrA is important both for adherence to and invasion of human INT407 epithelial cells |
-, 667253 |
| 3.4.21.107 | medicine |
htrA mutants can act as vaccines |
653255 |
| 3.4.21.107 | medicine |
HtrA1 is developmentally regulated in the uterus and trophoblast during placental establishment |
668373 |
| 3.4.21.107 | medicine |
HTRA1 is involved in osteoarthritis |
712536 |
| 3.4.21.107 | medicine |
human isoform HTRA1 degrades aggregated and fibrillar tau, a protein that is critically involved in various neurological disorders. Neuronal cells and patient brains accumulate less tau, neurofibrillary tangles, and neuritic plaques, respectively, when HTRA1 is expressed at elevated levels. HTRA1 mRNA and HTRA1 activity are up-regulated in response to elevated tau concentrations |
732058 |
| 3.4.21.107 | medicine |
increased expression of HtrA1 in the human placenta in the third trimester of gestation, especially in the outer layer forming the syncytiotrophoblast |
669699 |
