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2.7.1.150
drug development
potential for targeting this kinase in developing small-molecule antivirals against SARS-CoV-2. The infection is fully blocked by bafilomycin A1, which inhibits the vacuolar type H+-ATPase (V-ATPase) acidification activity. Apilimod and vacuolin-1 prevent cytoplasmic entry of VSV-MeGFP-ZEBOV (from Zaire ebolavirus VSV-ZEBOV)
762289
2.7.1.150
drug development
the enzyme is a potential target for developing small-molecule antivirals against SARS-CoV-2
762289
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