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EC Number	Application	Commentary	Reference
2.6.1.57	synthesis	asymmetric synthesis of L-homophenylalanine and L-phenylglycine from 2-oxo-4-phenylbutyrate and phenylglyoxylate, respectively, using L-glutamate as an amino donor. AroATBs can be used as a biocatalyst for the synthesis of unnatural L-amino acids by taking advantage of the large solubility difference between substrate and product at higher temperatures to accelerate an equilibrium shift favoring product formation	-, 672719
2.6.1.57	synthesis	asymmetric synthesis of the nonproteinogenic amino acids (2S)-2-amino-4-oxo-4-phenylbutyric and (3E,2S)-2-amino-4-phenylbutenoic acid by recombinant Escherichia coli whole cells overexpressing aromatic transaminase from Enterobacter sp. BK2K-1 (AroATEs) in high yields (6878%) and high enantiomeric purity (>99%) using L-aspartic acid as an amino donor	-, 677173
2.6.1.57	synthesis	deletion of the Aro8 gene stimulates phenylethanol production when combined with other mutations that deregulate aromatic amino acid biosynthesis, i.e. expression of phenylalanine and tyrosine feedback-insensitive DAHP synthase. The resulting engineered Saccharomyces cerevisiae strain produces more than 3 mM phenylethanol from glucose during growth on a simple synthetic medium	739763

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Release 2023.1 (January 2023)