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1.1.1.300
medicine
enzyme is associated with retinal dystrophy and encodes an enzyme with unique, nonredundant role in the photoreceptor cells
656851
1.1.1.300
medicine
transfection with retinol dehydrogenase 12 protects cells against nonanal-induced toxicity but is ineffective against 4-hydroxynonenal. 4-Hydroxynonenal strongly inhibits the activities of lecithin:retinol acyl transferase and aldehyde dehydrogenase, resulting in decreased levels of retinyl esters and retinoic acid and accumulation of unesterified retinol
685381
1.1.1.300
pharmacology
enzyme RDH8 is a therapeutic target for controlling bis-retinoid A2E cytotoxicity
761323
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