EC Number   |
Natural Substrates |
|---|
   1.14.13.8 | (S)-nicotine + NADPH + O2 |
(S)-nicotine N-1'-oxygenation |
| 1.14.13.8 | 1,1-dimethylhydrazine + NADPH + O2 |
possibly, and other 1,1-disubstituted hydrazines |
| 1.14.13.8 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 |
reaction in microsomal detoxification pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a neurotoxin to nigrostriatal dopaminergic neurons |
| 1.14.13.8 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 |
one of the predominant enzmyes responsible for the oxygenation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| 1.14.13.8 | 10-(N,N-dimethylaminopentyl)-2-(trifluoromethyl)phenothiazine + NADPH + O2 |
- |
| 1.14.13.8 | 10-N-(n-octylamino)-2-(trifluoromethyl) phenothiazine + NADPH + O2 |
- |
| 1.14.13.8 | 3-hydroxy-nabumetone + NADPH + H+ + O2 |
activation reaction |
| 1.14.13.8 | 4-aminobenzoic acid hydrazide + NADPH + O2 |
- |
| 1.14.13.8 | amphetamine + NADPH + O2 |
- |
| 1.14.13.8 | benzydamine + NADPH + H+ + O2 |
- |
