EC Number |
Localization |
GeneOntology No. |
Reference |
---|
3.4.21.109 | apical plasma membrane |
a proportion of matriptase-hepatocyte growth factor activator inhibitor-1 complexes, but not the latent matriptase, undergo transcytosis to the apical plasma membrane for secretion |
GO:0016324 AmiGO QuickGO |
707054 |
3.4.21.109 | apical plasma membrane |
matriptase C-terminal fragment molecules are delivered to both the apical and the basolateral side of Madin-Darby canine kidney cells |
GO:0016324 AmiGO QuickGO |
707786 |
3.4.21.109 | basolateral plasma membrane |
latent matriptase is localized at the basolateral surface of the ductal epithelial cells of prostate and kidney and in Caco-2 cells. The cells target latent matriptase to the basolateral plasma membrane where activation, inhibition, and secretion of matriptase take place |
GO:0016323 AmiGO QuickGO |
707054 |
3.4.21.109 | basolateral plasma membrane |
the N-terminal fragment part occurs on the basolateral side but poorly on the apical siden when expresssed in Madin-Darby canine kidney cells. Matriptase C-terminal fragment molecules are delivered to both the apical and the basolateral side of Madin-Darby canine kidney cells |
GO:0016323 AmiGO QuickGO |
707786 |
3.4.21.109 | cell surface |
- |
GO:0009986 AmiGO QuickGO |
657796, 673572, 675024, 683145, 683364, 683489, 683493, 683494, 683514, 683674, 731663 |
3.4.21.109 | cell surface |
acid-induced matriptase activation takes place both on the cell surface and inside the cells, likely due to the parallel intracellular acidification that activates intracellular matriptase |
GO:0009986 AmiGO QuickGO |
709136 |
3.4.21.109 | cell surface |
apical surface of epithelial cells |
GO:0009986 AmiGO QuickGO |
732419 |
3.4.21.109 | cell surface |
cell surface type II transmembrane protein |
GO:0009986 AmiGO QuickGO |
731410 |
3.4.21.109 | cell surface |
matriptase is activated when it reaches the cell surface |
GO:0009986 AmiGO QuickGO |
708947 |
3.4.21.109 | cell surface |
matriptase translocates to the cell surface and is activated within min after exposure of breast cancer cells to sphingosine-1-phosphate requiring actin cytoskeleton remodeling |
GO:0009986 AmiGO QuickGO |
683893 |