EC Number |
Inhibitors |
Structure |
---|
3.4.22.B78 | Ca2+ |
inhibits 29% at 5 mM, 19% at 1 mM |
|
3.4.22.B78 | Co2+ |
inhibits 74% at 0.2 mM and precipitates the enzyme at 1 mM |
|
3.4.22.B78 | Cu2+ |
inhibits 57% at 0.2 mM, 81% at 1 mM, and precipitates the enzyme at 5 mM |
|
3.4.22.B78 | Fe3+ |
inhibits 28% at 0.2 mM, 68% at 1 mM, and precipitates the enzyme at 5 mM |
|
3.4.22.B78 | iodoacetamide |
strong inhibition; strongly inhibits the peptidase activity, confirming that Cys100 is a nucleophilic residue |
|
3.4.22.B78 | K+ |
inhibits 19% at 5 mM |
|
3.4.22.B78 | Mg2+ |
inhibits 10% at 5 mM |
|
3.4.22.B78 | Mn2+ |
inhibits 81% at 5 mM, 42% at 1 mM |
|
3.4.22.B78 | Na+ |
inhibits 28% at 5 mM |
|
3.4.22.B78 | Ni2+ |
inhibits 85% at 0.2 mM and precipitates the enzyme at 1 mM |
|