EC Number |
Inhibitors |
Structure |
---|
1.1.1.47 | (NH4)2SO4 |
1 M, 71% inhibition |
|
1.1.1.47 | 2-mercaptoethanol |
1 mM, room temperature, pH 9.0, rapid inactivation |
|
1.1.1.47 | 3-(2-bromoacetyl)pyridine |
active-site-directed irreverseible inhibitor, the cofactor NAD but not the substrate glucose protects the enzyme from the inactivation, in the presence of 0.1 M NAD and 1.37 mM 3-(2-bromoacetyl)pyridine, glucose dehydrogenase has still 85% of its original activity after incubation for 2 h |
|
1.1.1.47 | 5,5'-dithiobis(2-nitrobenzoic acid) |
1 mM, room temperature, pH 9.0, 50% inactivation |
|
1.1.1.47 | acetone |
1% residual activity at 50% (v/v) |
|
1.1.1.47 | Ag+ |
1 mM, 99% inhibition |
|
1.1.1.47 | Ca2+ |
1 mM, 14% inhibition |
|
1.1.1.47 | Ca2+ |
1 mM, 33% inhibition |
|
1.1.1.47 | Ca2+ |
60% inhibition at 50, 100 and 10 mM in sodium phosphate buffer at pH 8.0, Tris/HCl buffer at pH 8.0 and Tris/HCl buffer at pH 9.0, respectively |
|
1.1.1.47 | Cd2+ |
more than 50% inhibition at 20 mM |
|