EC Number   |
Activating Compound |
Reference |
|---|
   1.4.3.13 | 5-aza-deoxycytidine |
activates LOXL2 gene expression |
686947 |
| 1.4.3.13 | actinomycin D |
- |
391737 |
| 1.4.3.13 | areca nut extract |
up-regulates LOX expression |
686141 |
| 1.4.3.13 | hypoxia inducible factor-1 |
hypoxia-induced LOX expression is partially mediated by hypoxia inducible factor-1 |
687920 |
| 1.4.3.13 | more |
active LOX promotes focal adhesion kinase activation and invasive/migratory behaviour of astrocytes |
689199 |
| 1.4.3.13 | more |
hypoxia/reoxygenation drives poorly invasive breast cancer cells toward a more aggressive phenotype by up-regulating LOX expression and catalytic activity |
687920 |
| 1.4.3.13 | more |
LOX regulates also the promoter of elastin und collagen III, treatment with tumor growth factor-beta1 and CTGF abolishes completely the activation induced by LOX |
688796 |
| 1.4.3.13 | more |
suramin has no influence on LOX expression |
685931 |
| 1.4.3.13 | more |
the lysyl oxidase gene is induced by quiescence in general rather than specific to serum deprivation |
686106 |
| 1.4.3.13 | more |
the transcriptional level of LOX is significantly upregulated in dilated cardiomyopathy hearts |
688955 |
