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Gene ontology
Version 2014-12-22
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Details for NADP-retinol dehydrogenase activity
1.1.1.300
Gene ontology ID
GO:0052650
Definition
Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+
Synonyms
1. all-trans retinal reductase activity
2. all-trans-retinol dehydrogenase activity
3. NADP(H)-dependent retinol dehydrogenase/reductase activity
4. retinol dehydrogenase [NADP+] activity
5. retinol:NADP+ oxidoreductase activity
References
1. RHEA: 25033
2. EC 1.1.1.300
3. KEGG REACTION: R08379
4. MetaCyc RXN-10841
5. Reactome: R-HSA-2464803 "RDH8 reduces atRAL to atROL"
6. Reactome: R-HSA-2464822 "RDH12 reduces atRAL to atROL"
7. Reactome: R-HSA-2465921 "11cRDH oxidises 11cROL to 11cRAL"
8. Reactome: R-HSA-2465940 "atRAL is reduced to atROL"
9. Reactome: R-HSA-2466861 "Defective RDH12 does not reduce atRAL to atROL and causes LCA13"
10. Reactome: R-HSA-2471670 "Defective RDH12 does not reduce atRAL to atROL"
11. Reactome: R-HSA-5419165 "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL"
12. Reactome: R-HSA-5615668 "AKR1C3 reduces atRAL to atROL"
13. Reactome: R-HSA-5623643 "RDH13 reduces atRAL to atROL"
14. Reactome: R-HSA-74872 "RDH10,11 oxidise 11cROL to 11cRAL"
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