Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

Id:

restrict to BRENDA links:

Localization

Enzyme

Details for prostaglandin-E synthase activity

5.3.99.3

Gene ontology ID

GO:0050220

Definition

Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2)

Synonyms

1. (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity
2. endoperoxide isomerase activity
3. PGE isomerase activity
4. PGE2 isomerase activity
5. PGH-PGE isomerase activity
6. prostaglandin endoperoxide E isomerase activity
7. prostaglandin endoperoxide E2 isomerase activity
8. prostaglandin H-E isomerase activity
9. prostaglandin R-prostaglandin E isomerase activity
10. Prostaglandin-H(2) E-isomerase activity
11. prostaglandin-H2 E-isomerase activity

References

1. EC 5.3.99.3
2. RHEA: 12893
3. KEGG REACTION: R02265
4. MetaCyc PROSTAGLANDIN-E-SYNTHASE-RXN
5. Reactome: R-HSA-2161660 "PGH2 is isomerised to PGE2 by PTGES"
6. Reactome: R-HSA-265295 "Prostaglandin E synthase isomerizes PGH2 to PGE2"

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

molecular_function is a

catalytic activity is a

isomerase activity is a

intramolecular oxidoreductase activity is a

prostaglandin-E synthase activity is a

Tree view

Gene ontology

biological_process is a

cellular_component is a

molecular_function is a

binding

catalytic activity is a

catalytic activity, acting on a protein is a

catalytic activity, acting on DNA is a

catalytic activity, acting on RNA is a

cyclase activity is a

hydrolase activity is a

isomerase activity is a

(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity is a

4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity is a

cis-trans isomerase activity is a

dihydroneopterin triphosphate 2'-epimerase activity is a

eoxin A4 synthase activity is a

hepoxilin A3 synthase activity is a

hexulose-6-phosphate isomerase activity is a

intramolecular lyase activity is a

intramolecular oxidoreductase activity is a

2-carboxy-2-hydroxy-8-carboxychromene isomerase activity is a

2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity is a

2-hydroxy-8-methylchromene-2-carboxylate isomerase activity is a

2-hydroxychromene-2-carboxylate isomerase activity is a

2-hydroxytetrahydrofuran isomerase activity is a

capsanthin synthase activity is a

capsorubin synthase activity is a

intramolecular oxidoreductase activity, interconverting aldoses and ketoses is a

intramolecular oxidoreductase activity, interconverting keto- and enol-groups is a

intramolecular oxidoreductase activity, transposing C=C bonds is a

intramolecular oxidoreductase activity, transposing S-S bonds is a

lachrymatory factor synthase activity is a

neoxanthin synthase activity is a

prostaglandin-D synthase activity is a

prostaglandin-E synthase activity is a

prostaglandin-I synthase activity is a

styrene-oxide isomerase activity is a

thromboxane-A synthase activity is a

intramolecular transferase activity is a

N-acylmannosamine-6-phosphate 2-epimerase activity is a

peroxynitrite isomerase activity is a

racemase and epimerase activity is a

sulfoquinovose isomerase activity is a

thiocyanate isomerase activity is a

ligase activity is a

lyase activity is a

peptidoglycan muralytic activity is a

transferase activity is a

molecular transducer activity is a

nutrient reservoir activity is a

protein tag is a

small molecule sensor activity is a

structural molecule activity is a

transcription regulator activity is a

transporter activity is a