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Gene ontology
Version 2014-12-22
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Details for N-acetylgalactosamine-6-sulfatase activity
3.1.6.4
Gene ontology ID
GO:0043890
Definition
Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate
Synonyms
1. acetylgalactosamine 6-sulfatase activity
2. chondroitin sulfatase
3. chondroitinase
4. chondroitinsulfatase
5. galactose-6-sulfate sulfatase activity
6. N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity
7. N-acetylgalactosamine 6-sulfatase activity
8. N-acetylgalactosamine-6-sulfate sulfatase activity
References
1. EC 3.1.6.4
2. MetaCyc 3.1.6.4-RXN
3. Reactome: R-HSA-1630304 "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate"
4. Reactome: R-HSA-2263490 "Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate"
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