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Gene ontology
Version 2014-12-22
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Details for glutathione hydrolase activity
3.4.19.13
Gene ontology ID
GO:0036374
Definition
Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate
Synonyms
1. gamma-glutamyltranspeptidase activity
2. glutathionase activity
References
1. EC 3.4.19.13
2. GOC: imk
3. KEGG REACTION: R00494
4. MetaCyc RXN-12618
5. Reactome: R-HSA-1222712 "Nitrosoglutathione gets cleaved to Cys(NO)-Gly"
6. Reactome: R-HSA-266046 "GGT1, 5 dimers hydrolyse LTC4 to LTD4"
7. Reactome: R-HSA-5433072 "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG"
8. Reactome: R-HSA-5602984 "Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG"
9. Reactome: R-HSA-8943279 "GGT dimers hydrolyse GSH"
10. Reactome: R-HSA-9026757 "GGT hydrolyses MCTR1 to MCTR2"
11. Reactome: R-HSA-9026907 "GGT hydrolyses PCTR2 to PCTR3"
12. Reactome: R-HSA-9026912 "GGT hydrolyses PCTR1 to PCTR2"
13. Reactome: R-HSA-9026916 "GGT hydrolyses RCTR2 to RCTR3"
14. Reactome: R-HSA-9026927 "GGT hydrolyses RCTR1 to RCTR2"
15. Reactome: R-HSA-9035966 "Defective GGT1 does not hydrolyse GSH"
16. RHEA: 28807
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