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Gene ontology
Version 2014-12-22
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Details for cholesterol 24-hydroxylase activity
1.14.14.25
Gene ontology ID
GO:0033781
Definition
Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+)
Synonyms
1. cholesterol 24-monooxygenase activity
2. cholesterol 24S-hydroxylase activity
3. cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity
4. CYP46
5. CYP46A1
6. cytochrome P450 46A1
References
1. EC 1.14.14.25
2. RHEA: 22716
3. KEGG REACTION: R07207
4. MetaCyc 1.14.13.98-RXN
5. Reactome: R-HSA-192061 "CYP46A1 24-hydroxylates CHOL"
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