Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for dihydropyrimidine dehydrogenase (NADP+) activity
1.3.1.2
Gene ontology ID
GO:0017113
Definition
Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+
Synonyms
1. 4,5-dihydrothymine: oxidoreductase activity
2. 5,6-dihydrouracil:NADP+ 5-oxidoreductase activity
3. dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)
4. DHPDH
5. DHU dehydrogenase activity
6. dihydropyrimidine dehydrogenase activity
7. dihydrothymine dehydrogenase activity
8. dihydrouracil dehydrogenase (NADP)
9. dihydrouracil dehydrogenase (NADP+) activity
10. DPD
11. hydropyrimidine dehydrogenase activity
References
1. EC 1.3.1.2
2. MetaCyc 1.3.1.2-RXN
3. Reactome: R-HSA-73585 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+"
4. Reactome: R-HSA-73616 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+"
5. RHEA: 18093
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
metabolic process is a
oxidation-reduction process is a
oxidoreductase activity part of
oxidoreductase activity, acting on the CH-CH group of donors is a
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor is a
dihydropyrimidine dehydrogenase (NADP+) activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
adaptive thermogenesis is a
ATP metabolic process is a
biosynthetic process is a
catabolic process is a
collagen metabolic process is a
demethylation is a
glycosylation is a
hydrogen metabolic process is a
methylation is a
multi-organism metabolic process is a
NAD metabolic process is a
NADH metabolic process is a
NADP metabolic process is a
nitrogen compound metabolic process is a
organic substance metabolic process is a
oxidation-reduction process is a
iodide oxidation is a
oxidative deethylation is a
oxidoreductase activity part of
1,1,1-trichloroethane reductive dehalogenase activity is a
1,1,2-trichloroethene reductive dehalogenase activity is a
1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity is a
1,1-dichloroethane reductive dehalogenase activity is a
1,2-dichloroethene reductive dehalogenase activity is a
2,4-dichloroaniline reductive dehalogenase activity is a
2,4-dichlorophenoxyacetate dehalogenase activity is a
2,5-dichlorohydroquinone reductive dehalogenase activity is a
2-chloro-N-isopropylacetanilide reductive dehalogenase activity is a
2-octaprenylphenol hydroxylase activity is a
2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity is a
3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity is a
3,3',5-tribromobisphenol A reductive dehalogenase activity is a
3,3'-dibromobisphenol A reductive dehalogenase activity is a
3,8-divinyl protochlorophyllide a 8-vinyl reductase activity is a
3-monobromobisphenol A reductive dehalogenase activity is a
alpha-ketoacid dehydrogenase activity is a
arsenate reductase activity is a
chlorate reductase activity is a
chromate reductase activity is a
crotonyl-CoA reductase activity is a
delta1-piperideine-6-carboxylate dehydrogenase activity is a
dihydronicotinamide riboside quinone reductase activity is a
dihydropterin oxidase activity is a
dimethylarsinate reductase activity is a
dioxygenase activity is a
epoxyqueuosine reductase activity is a
fatty acid alpha-hydroxylase activity is a
geranylgeranyl reductase activity is a
glycyl-radical enzyme activating activity is a
heme-copper terminal oxidase activity is a
hydroxymethylbutenyl pyrophosphate reductase activity is a
malolactic enzyme activity is a
monooxygenase activity is a
NADPH-adrenodoxin reductase activity is a
NADPH:sulfur oxidoreductase activity is a
ortho-trichlorophenol reductive dehalogenase activity is a
oxidoreductase activity, acting on a heme group of donors is a
oxidoreductase activity, acting on a sulfur group of donors is a
oxidoreductase activity, acting on CH or CH2 groups is a
oxidoreductase activity, acting on CH-OH group of donors is a
oxidoreductase activity, acting on diphenols and related substances as donors is a
oxidoreductase activity, acting on halogen in donors is a
oxidoreductase activity, acting on hydrogen as donor is a
oxidoreductase activity, acting on iron-sulfur proteins as donors is a
oxidoreductase activity, acting on NAD(P)H is a
oxidoreductase activity, acting on other nitrogenous compounds as donors is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is a
oxidoreductase activity, acting on peroxide as acceptor is a
oxidoreductase activity, acting on phosphorus or arsenic in donors is a
oxidoreductase activity, acting on reduced flavodoxin as donor is a
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is a
oxidoreductase activity, acting on superoxide radicals as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors is a
oxidoreductase activity, acting on the CH-CH group of donors is a
(R)-benzylsuccinyl-CoA dehydrogenase activity is a
1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity is a
1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity is a
1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity is a
2,4,4-trimethylpentanoyl-CoA dehydrogenase activity is a
2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity is a
2-furoyl-CoA dehydrogenase activity is a
2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity is a
2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity is a
2-methylhexanoyl-CoA dehydrogenase activity is a
24-methyldesmosterol reductase activity is a
4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity is a
4-methyloctanoyl-CoA dehydrogenase activity is a
acyl-CoA dehydrogenase activity is a
carvone reductase activity is a
cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity is a
cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity is a
coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity is a
coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity is a
coenzyme F420-dependent 2,4-dinitrophenol reductase activity is a
coproporphyrinogen dehydrogenase activity is a
cyclohexanone dehydrogenase activity is a
isoquinoline 1-oxidoreductase activity is a
naphthyl-2-methyl-succinyl-CoA dehydrogenase activity is a
oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor is a
(+)-pulegone reductase, (+)-isomenthone as substrate, activity is a
(+)-pulegone reductase, (-)-menthone as substrate, activity is a
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity is a
1,2-dihydrovomilenine reductase activity is a
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity is a
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity is a
1-penten-3-one reductase activity is a
11-hydroxythromboxane B2 dehydrogenase activity is a
12-hydroxyheptadecatrienoic acid synthase activity is a
12-oxophytodienoate reductase activity is a
15-oxoprostaglandin 13-oxidase activity is a
2'-hydroxydaidzein reductase activity is a
2'-hydroxyisoflavone reductase activity is a
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity is a
2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity is a
2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity is a
2,4-dichlorobenzoyl-CoA reductase activity is a
2,4-dienoyl-CoA reductase (NADPH) activity is a
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity is a
2-alkenal reductase [NAD(P)+] activity is a
2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity is a
2-chloroacrylate reductase activity is a
2-coumarate reductase activity is a
2-enoate reductase activity is a
2-hexadecenal reductase activity is a
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity is a
2-methyl-branched-chain-enoyl-CoA reductase activity is a
22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity is a
24-epi-campsterol desaturase activity is a
3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity is a
3-methyleneoxindole reductase activity is a
4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity is a
4-hydroxy-tetrahydrodipicolinate reductase is a
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity is a
7-dehydrocholesterol reductase activity is a
acrolein reductase activity is a
acryloyl-CoA reductase (NADP+) activity is a
acryloyl-CoA reductase activity is a
acyl-CoA dehydrogenase (NADP+) activity is a
all-trans-geranyl-geranyl diphosphate reductase activity is a
alpha-santonin 1,2-reductase activity is a
anthocyanidin reductase activity is a
arogenate dehydrogenase [NAD(P)+] activity is a
benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity is a
benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity is a
beta-nitroacrylate reductase activity is a
biliverdin reductase activity is a
biochanin-A reductase activity is a
but-1-en-3-one reductase activity is a
campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity is a
cinnamate reductase activity is a
cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity is a
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity is a
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity is a
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity is a
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity is a
cis-2,3-dihydrodiol DDT dehydrogenase activity is a
cis-2-enoyl-CoA reductase (NADPH) activity is a
cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity is a
cis-chlorobenzene dihydrodiol dehydrogenase activity is a
cis-dihydroethylcatechol dehydrogenase activity is a
citronellyl-CoA dehydrogenase activity is a
cortisone alpha-reductase activity is a
crotonaldehyde redutase activity is a
cucurbitacin delta23-reductase activity is a
cyclohexadienyl dehydrogenase activity is a
delta14-sterol reductase activity is a
delta24(24-1) sterol reductase activity is a
delta24-sterol reductase activity is a
dibenzothiophene dihydrodiol dehydrogenase activity is a
dihydrogeranylgeranyl-chlorophyll a reductase activity is a
dihydrogeranylgeranyl-PP reductase activity is a
dihydropyrimidine dehydrogenase (NADP+) activity is a
dihydrouracil dehydrogenase (NAD+) activity is a
divinyl chlorophyllide a 8-vinyl-reductase activity is a
enone reductase activity is a
enoyl-[acyl-carrier-protein] reductase (NADH) activity is a
enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity is a
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity is a
enoyl-[acyl-carrier-protein] reductase activity is a
fumarate reductase (NADH) activity is a
furaneol oxidoreductase activity is a
geissoschizine dehydrogenase activity is a
geranylgeranyl diphosphate reductase activity is a
geranylgeranyl-chlorophyll a reductase activity is a
homofuraneol oxidoreductase activity is a
kynurenate-7,8-dihydrodiol dehydrogenase activity is a
lariciresinol reductase activity is a
maleylacetate reductase activity is a
menthone dehydrogenase activity is a
meso-tartrate dehydrogenase activity is a
N-ethylmaleimide reductase activity is a
NADPH-dependent curcumin reductase activity is a
NADPH-dependent dihydrocurcumin reductase activity is a
orotate reductase (NADH) activity is a
orotate reductase (NADPH) activity is a
phloroglucinol reductase activity is a
phosphatidylcholine desaturase activity is a
phthalate 3,4-cis-dihydrodiol dehydrogenase activity is a
phthalate 4,5-cis-dihydrodiol dehydrogenase activity is a
pimeloyl-CoA dehydrogenase activity is a
pinoresinol reductase activity is a
polyprenol reductase activity is a
precorrin-2 dehydrogenase activity is a
precorrin-6A reductase activity is a
prephenate dehydrogenase (NAD+) activity is a
prephenate dehydrogenase (NADP+) activity is a
progesterone 5-alpha-reductase activity is a
progesterone 5beta- reductase activity is a
protochlorophyllide reductase activity is a
pterocarpan reductase activity is a
tetrahydrogeranylgeranyl-chlorophyll a reductase activity is a
tetrahydrogeranylgeranyl-PP reductase activity is a
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity is a
trans-1,2-dihydrodiolphenanthrene dehydrogenase activity is a
trans-2-enoyl-CoA reductase (NAD+) activity is a
trans-2-enoyl-CoA reductase (NADPH) activity is a
trans-4-hexen-3-one reductase activity is a
trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity is a
trans-arachidon-2-enoyl-CoA reductase activity is a
trans-cerot-2-enoyl-CoA reductase activity is a
trans-docosan-2-enoyl-CoA reductase activity is a
trans-lignocero-2-enoyl-CoA reductase activity is a
very-long-chain enoyl-CoA reductase activity is a
xanthommatin reductase activity is a
zeatin reductase activity is a
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor is a
peptidyl-oxazoline dehydrogenase activity is a
peptidyl-thiazoline dehydrogenase activity is a
phytoene dehydrogenase activity is a
propionyl-CoA dehydrogenase activity is a
protoporphyrinogen oxidase activity is a
quinaldate 4-oxidoreductase activity is a
quinoline 2-oxidoreductase activity is a
quinoline-4-carboxylate 2-oxidoreductase activity is a
steroid dehydrogenase activity, acting on the CH-CH group of donors is a
sterol 5-alpha reductase activity is a
sterol delta7 reductase activity is a
succinate dehydrogenase activity is a
thalian-diol desaturase activity is a
thiol-driven fumarate reductase activity is a
oxidoreductase activity, acting on the CH-NH group of donors is a
oxidoreductase activity, acting on the CH-NH2 group of donors is a
oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond is a
oxidoreductase activity, oxidizing metal ions is a
oxygen evolving activity is a
perchlorate reductase activity is a
phthalate dioxygenase reductase activity is a
pyrogallol hydroxytransferase activity is a
reduced coenzyme F420 dehydrogenase activity is a
reduced coenzyme F420 oxidase activity is a
reduced coenzyme F420:quinone oxidoreductase activity is a
selenate reductase activity is a
sphingosine hydroxylase activity is a
steroid dehydrogenase activity is a
sulfur oxygenase reductase activity is a
sulfur reductase activity is a
tetrachloroethene reductive dehalogenase activity is a
tetrahydrothiophene 1-oxide reductase activity is a
thyroxine 5'-deiodinase activity is a
thyroxine 5-deiodinase activity is a
trimethylarsine oxidase activity is a
tyramine-beta hydroxylase activity is a
uracil oxygenase activity is a
vinyl chloride reductive dehalogenase activity is a
violaxanthin de-epoxidase activity is a
thioredoxin reduction is a
pigment metabolic process is a
primary metabolic process is a
respiratory burst is a
secondary metabolic process is a
small molecule metabolic process is a
tartrate metabolic process is a
tyrocidine metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a