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Gene ontology
Version 2014-12-22
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Details for tRNA (cytosine-5-)-methyltransferase activity
2.1.1.29
Gene ontology ID
GO:0016428
Definition
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine
Synonyms
1. S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity
2. transfer ribonucleate cytosine 5-methyltransferase activity
3. transfer RNA cytosine 5-methyltransferase activity
References
1. EC 2.1.1.29
2. Reactome: R-HSA-6782388 "NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA)"
3. Reactome: R-HSA-6782419 "TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp)"
4. Reactome: R-HSA-6785409 "NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC)"
5. Reactome: R-HSA-6785438 "NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC)"
6. Reactome: R-HSA-8932765 "NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr)"
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