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Gene ontology
Version 2014-12-22
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Details for phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
3.1.3.67
Gene ontology ID
GO:0016314
Definition
Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate
Synonyms
1. 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity
2. MMAC1
3. phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity
4. PI(3)P 3-phosphatase activity
5. PI(3,4,5)P3 3-phosphatase activity
6. PtdIns(3,4,5)P3 3-phosphatase activity
References
1. EC 3.1.3.67
2. MetaCyc 3.1.3.67-RXN
3. Reactome: R-HSA-199456 "PTEN dephosphorylates PIP3"
4. Reactome: R-HSA-202237 "Hydrolysis of PIP3 to PI(3,4)P2"
5. Reactome: R-HSA-2317387 "PTEN cancer mutants do not dephosphorylate PIP3"
6. RHEA: 25017
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
phosphorus metabolic process is a
phosphate-containing compound metabolic process is a
dephosphorylation is a
phosphatase activity part of
phosphatidylinositol phosphate phosphatase activity is a
phosphatidylinositol trisphosphate phosphatase activity is a
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
cellular biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
2-aminoethylphosphonate metabolic process is a
organophosphate metabolic process is a
phosphate-containing compound metabolic process is a
dephosphorylation is a
DNA dephosphorylation is a
phosphatase activity part of
10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity is a
2-carboxy-D-arabinitol-1-phosphatase activity is a
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity is a
2-phosphosulfolactate phosphatase activity is a
3',5'-nucleotide bisphosphate phosphatase activity is a
3-deoxy-manno-octulosonate-8-phosphatase activity is a
3-phosphoglycerate phosphatase activity is a
3-phytase activity is a
4-phytase activity is a
5'-deoxynucleotidase activity is a
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity is a
5-phytase activity is a
6-phosophogluco-3-phosphogluco-starch phosphatase activity is a
acid phosphatase activity is a
acireductone synthase activity is a
ADP-phosphoglycerate phosphatase activity is a
alkaline phosphatase activity is a
alkylacetylglycerophosphatase activity is a
alpha-ribazole phosphatase activity is a
aryldialkylphosphatase activity is a
bisphosphoglycerate phosphatase activity is a
caldesmon-phosphatase activity is a
carbohydrate phosphatase activity is a
D,D-heptose 1,7-bisphosphate phosphatase activity is a
deoxynucleotide 3'-phosphatase activity is a
dihydrosphingosine-1-phosphate phosphatase activity is a
dolichyl-phosphatase activity is a
ecdysone-phosphate phosphatase activity is a
ecdysteroid-phosphate phosphatase activity is a
FMN hydrolase activity is a
FMN phosphatase activity is a
fructose-1-phosphatase activity is a
glucosylglycerol 3-phosphatase activity is a
glycerol-1-phosphatase activity is a
glycerol-2-phosphatase activity is a
glycerol-3-phosphatase activity is a
guanidinodeoxy-scyllo-inositol-4-phosphatase activity is a
histidinol-phosphatase activity is a
inositol phosphate phosphatase activity is a
L-threonine O-3-phosphate phosphatase activity is a
lipid phosphatase activity is a
lysophosphatidic acid phosphatase activity is a
mannitol-1-phosphatase activity is a
mannosyl-3-phosphoglycerate phosphatase activity is a
methylphosphothioglycerate phosphatase activity is a
N-acylneuraminate-9-phosphatase activity is a
NADP phosphatase activity is a
NADPH phosphatase activity is a
NMN phosphatase activity is a
nucleotidase activity is a
nucleotide phosphatase activity, acting on free nucleotides is a
phosphatidate phosphatase activity is a
phosphatidylglycerophosphatase activity is a
phosphatidylinositol phosphate phosphatase activity is a
phosphatidylinositol bisphosphate phosphatase activity is a
phosphatidylinositol monophosphate phosphatase activity is a
phosphatidylinositol phosphate 4-phosphatase activity is a
phosphatidylinositol phosphate 5-phosphatase activity is a
phosphatidylinositol trisphosphate phosphatase activity is a
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity is a
phosphatidylinositol-5-phosphate 5-phosphatase activity is a
phosphocholine phosphatase activity is a
phosphoenolpyruvate phosphatase activity is a
phosphoethanolamine phosphatase activity is a
phosphoglycerate phosphatase activity is a
phosphoglycolate phosphatase activity is a
phosphoserine phosphatase activity is a
pseudouridine 5'-phosphatase activity is a
pyridoxal phosphatase activity is a
ribitol-5-phosphatase activity is a
sedoheptulose-bisphosphatase activity is a
sorbitol-6-phosphatase activity is a
streptomycin-6-phosphatase activity is a
thymidylate 5'-phosphatase activity is a
phosphoanandamide dephosphorylation is a
polynucleotide 3' dephosphorylation is a
polynucleotide 5' dephosphorylation is a
phosphorylation is a
phosphorus utilization
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a