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Gene ontology
Version 2014-12-22
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Details for ATPase-coupled vitamin B12 transmembrane transporter activity
7.6.2.8
Gene ontology ID
GO:0015420
Definition
Catalysis of the reaction: ATP(4-) + cob(I)alamin + H2O <=> ADP(3-) + hydrogenphosphate + cob(I)alamin + H+. Cobalamin is also known as vitamin B12
Synonyms
1. ATP-dependent cobalamin transmembrane transporter activity
2. ATP-dependent vitamin B12 transmembrane transporter activity
3. ATPase-coupled cobalamin transmembrane transporter activity
4. cobalamin ABC transporter
5. cobalamin porter activity
6. cobalamin transporter activity
7. cobalamin-transporting ATPase activity
8. vitamin B12 ABC transporter activity
9. vitamin B12 porter activity
10. vitamin B12 transporter activity
11. vitamin B12-transporting ATPase activity
References
1. EC 7.6.2.8
2. GOC: pz
3. MetaCyc 3.6.3.33-RXN
4. MetaCyc ABC-5-RXN
5. Reactome: R-HSA-3000122 "CD320 transports extracellular TCII:Cbl to endosome"
6. Reactome: R-HSA-3000238 "LMBRD1 transports lysosomal Cbl to cytosol"
7. Reactome: R-HSA-3095901 "ABCC1 transports cytosolic Cbl to extracellular region"
8. Reactome: R-HSA-3315437 "Defective LMBRD1 does not transport lysosomal Cbl to cytosol"
9. RHEA: 17873
10. RHEA: 32831
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