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Gene ontology
Version 2014-12-22
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Details for N-acetylneuraminate lyase activity
4.1.3.3
Gene ontology ID
GO:0008747
Definition
Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate
Synonyms
1. acetylneuraminate lyase activity
2. acetylneuraminate pyruvate-lyase activity
3. N-acetylneuraminate aldolase activity
4. N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
5. N-acetylneuraminate pyruvate-lyase activity
6. N-acetylneuraminic acid aldolase activity
7. N-acetylneuraminic acid lyase activity
8. N-acetylneuraminic aldolase activity
9. N-acetylneuraminic lyase activity
10. NALase activity
11. NANA lyase activity
12. neuraminate aldolase activity
13. neuraminic acid aldolase activity
14. neuraminic aldolase activity
15. NPL
16. sialate lyase activity
17. sialic acid aldolase activity
18. sialic aldolase activity
References
1. EC 4.1.3.3
2. RHEA: 23296
3. KEGG REACTION: R01811
4. MetaCyc ACNEULY-RXN
5. Reactome: R-HSA-4085217 "NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
lyase activity is a
carbon-carbon lyase activity is a
oxo-acid-lyase activity is a
N-acetylneuraminate lyase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity is a
alkylmercury lyase activity is a
carbon phosphorus lyase activity is a
carbon-carbon lyase activity is a
(1-methylpentyl)succinate synthase activity is a
2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA lyase activity is a
3,4-dihydroxy-2-butanone-4-phosphate synthase activity is a
aldehyde decarbonylase activity is a
aldehyde oxygenase (deformylating) activity is a
aldehyde-lyase activity is a
benzylsuccinate synthase activity is a
carboxy-lyase activity is a
GTP 3',8'-cyclase activity is a
oxo-acid-lyase activity is a
(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity is a
(2Z)-2,4-dihydroxydec-2-enedioate aldolase activity is a
(4S)-4-hydroxy-2-oxoglutarate aldolase activity is a
(R)-citramalyl-CoA lyase activity is a
(S)-citramalyl-CoA lyase activity is a
1,4-dihydroxy-2-naphthoyl-CoA synthase activity is a
2,3-dimethylmalate lyase activity is a
3-hydroxy-3-isohexenylglutaryl-CoA lyase activity is a
3-hydroxyaspartate aldolase activity is a
4-amino-4-deoxychorismate lyase activity is a
4-hydroxy-2-oxovalerate aldolase activity is a
4-hydroxy-4-methyl-2-oxoglutarate aldolase activity is a
5-chloro-4-hydroxy-2-oxopentanate aldolase activity is a
anthranilate synthase activity is a
chorismate lyase activity is a
cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity is a
citramalate lyase activity is a
citrate (pro-3S)-lyase activity is a
citryl-CoA lyase activity is a
hydroxymethylglutaryl-CoA lyase activity is a
isocitrate lyase activity is a
L-erythro-3-methylmalyl-CoA lyase activity is a
malyl-CoA lyase activity is a
methylisocitrate lyase activity is a
N-acetylneuraminate lyase activity is a
oxalomalate lyase activity is a
straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity is a
tyrosine phenol-lyase activity is a
carbon-halide lyase activity is a
carbon-nitrogen lyase activity is a
carbon-oxygen lyase activity is a
carbon-sulfur lyase activity is a
cobalt-precorrin-5A acetaldehyde-lyase activity is a
ferrochelatase activity is a
indoleacetaldoxime dehydratase activity is a
phosphorus-oxygen lyase activity is a
sirohydrochlorin cobaltochelatase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a