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Gene ontology
Version 2014-12-22
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Details for alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
2.4.1.143
Gene ontology ID
GO:0008455
Definition
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R
Synonyms
1. acetylglucosaminyltransferase II activity
2. alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity
3. alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity
4. alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity
5. GnTII activity
6. N-acetylglucosaminyltransferase II activity
7. N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity
8. UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity
9. UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity
10. UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity
11. uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity
12. uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity
13. uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity
14. uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity
15. uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity
References
1. EC 2.4.1.143
2. MetaCyc 2.4.1.143-RXN
3. Reactome: R-HSA-4793955 "Defective MGAT2 does not transfer GlcNAc to N-glycans"
4. Reactome: R-HSA-975829 "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2"
5. RHEA: 12941
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on a glycoprotein is a
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
alpha-1,4-glucan-protein synthase (ADP-forming) activity is a
biotin-protein ligase activity is a
catalytic activity, acting on a glycoprotein is a
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity is a
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity is a
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity is a
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity is a
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity is a
alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity is a
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity is a
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity is a
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity is a
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity is a
galactosylxylosylprotein 3-beta-galactosyltransferase activity is a
glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity is a
glycopeptide alpha-N-acetylgalactosaminidase activity is a
glycoprotein N-palmitoyltransferase activity is a
glycoprotein O-fatty-acyltransferase activity is a
glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity is a
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity is a
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity is a
xylosylprotein 4-beta-galactosyltransferase activity is a
deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity is a
dihydrolipoyllysine-residue acetyltransferase activity is a
dihydrolipoyllysine-residue succinyltransferase activity is a
GPI-anchor transamidase activity is a
lipoate-protein ligase activity is a
peptidyl-aspartic acid 3-dioxygenase activity is a
peptidyl-lysine N6-palmitoyltransferase activity is a
peptidylamidoglycolate lyase activity is a
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity is a
polypeptide N-acetylgalactosaminyltransferase activity is a
procollagen galactosyltransferase activity is a
procollagen glucosyltransferase activity is a
protein disulfide isomerase activity is a
protein methylesterase activity is a
protein methylthiotransferase activity is a
protein N-acetylglucosaminyltransferase activity is a
protein O-GlcNAc transferase activity is a
protein prenyltransferase activity is a
protein xylosyltransferase activity is a
protein-cysteine S-acyltransferase activity is a
protein-fructosamine 3-kinase activity is a
protein-glucosylgalactosylhydroxylysine glucosidase activity is a
protein-glutamic acid ligase activity is a
protein-glycine ligase activity is a
protein-ribulosamine 3-kinase activity is a
protein-tyrosine sulfotransferase activity is a
Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity is a
transferase activity, transferring amino-acyl groups is a
tubulin-tyrosine ligase activity is a
ubiquitin-like protein transferase activity is a
ubiquitinyl hydrolase activity is a
[acyl-carrier-protein] phosphodiesterase activity is a
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase is a
[protein-PII] uridylyltransferase activity is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a