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Gene ontology
Version 2014-12-22
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Details for phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
6.3.2.6
Gene ontology ID
GO:0004639
Definition
Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate
Synonyms
1. 4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity
2. 4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity
3. 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity
4. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)
5. 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity
6. phosphoribosylaminoimidazole-succinocarboxamide synthase activity
7. phosphoribosylaminoimidazole-succinocarboxamide synthetase activity
8. phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity
9. PurC
10. SAICAR synthase activity
11. SAICAR synthetase activity
12. SAICARs activity
References
1. EC 6.3.2.6
2. RHEA: 22628
3. KEGG REACTION: R04591
4. MetaCyc SAICARSYN-RXN
5. Reactome: R-HSA-73805 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi"
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