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Gene ontology
Version 2014-12-22
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Details for squalene monooxygenase activity
1.14.14.17
Gene ontology ID
GO:0004506
Definition
Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+)
Synonyms
1. squalene 2,3-oxidocyclase activity
2. squalene epoxidase activity
3. squalene hydroxylase activity
4. squalene oxydocyclase activity
5. squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity
6. squalene-2,3-epoxidase activity
7. squalene-2,3-epoxide cyclase activity
References
1. RHEA: 25282
2. EC 1.14.14.17
3. KEGG REACTION: R02874
4. MetaCyc SQUALENE-MONOOXYGENASE-RXN
5. Reactome: R-HSA-191299 "Squalene is oxidized to its epoxide"
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