Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for leukotriene-C4 synthase activity
4.4.1.20
Gene ontology ID
GO:0004464
Definition
Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4)
Comment
Note that this function was EC:2.5.1.37.
Synonyms
1. (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)
2. (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)
3. leukotriene A(4):glutathione S-leukotrienyltransferase activity
4. leukotriene A4:glutathione S-leukotrienyltransferase activity
5. leukotriene C(4) synthetase activity
6. leukotriene C4 synthetase activity
7. leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)
8. LTC(4) synthase activity
9. LTC(4) synthetase activity
10. LTC4 synthase activity
11. LTC4 synthetase activity
References
1. EC 4.4.1.20
2. RHEA: 17617
3. KEGG REACTION: R03059
4. MetaCyc LEUKOTRIENE-C4-SYNTHASE-RXN
5. Reactome: R-HSA-266050 "LTA4 is converted to LTC4 by LTC4S"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
lyase activity is a
carbon-sulfur lyase activity is a
leukotriene-C4 synthase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity is a
alkylmercury lyase activity is a
carbon phosphorus lyase activity is a
carbon-carbon lyase activity is a
carbon-halide lyase activity is a
carbon-nitrogen lyase activity is a
carbon-oxygen lyase activity is a
carbon-sulfur lyase activity is a
2-hydroxypropyl-CoM lyase activity is a
2-mercaptobenzothiazole desulfurase activity is a
alliin lyase activity is a
cystathionine beta-lyase activity is a
cystathionine gamma-lyase activity is a
cysteine lyase activity is a
cysteine sulfinate desulfinase activity is a
cysteine-S-conjugate beta-lyase activity is a
D-cysteine desulfhydrase activity is a
dimethylpropiothetin dethiomethylase activity is a
eoxin C4 synthase activity is a
hercynylselenocysteine lyase activity (selenoneine-forming) is a
holocytochrome-c synthase activity is a
homocysteine desulfhydrase activity is a
L-3-cyanoalanine synthase activity is a
L-cysteate sulfo-lyase activity is a
L-cysteine desulfhydrase activity is a
L-cystine L-cysteine-lyase (deaminating) is a
lactoylglutathione lyase activity is a
leukotriene-C4 synthase activity is a
methionine gamma-lyase activity is a
methylselenocysteine deselenhydrase activity is a
phosphosulfolactate synthase activity is a
S-(hydroxymethyl)glutathione synthase activity is a
S-alkylcysteine lyase activity is a
S-alkylthiohydroximate lyase activity is a
S-ribosylhomocysteine lyase activity is a
selenocystathionine gamma-lyase activity is a
selenocysteine lyase activity is a
selenomethionine gamma-lyase activity is a
sulfoacetaldehyde lyase activity is a
sulfolactate sulfo-lyase activity is a
cobalt-precorrin-5A acetaldehyde-lyase activity is a
ferrochelatase activity is a
indoleacetaldoxime dehydratase activity is a
phosphorus-oxygen lyase activity is a
sirohydrochlorin cobaltochelatase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a