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Gene ontology
Version 2014-12-22
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Details for iduronate-2-sulfatase activity
3.1.6.13
Gene ontology ID
GO:0004423
Definition
Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin
Synonyms
1. 2-sulfo-L-iduronate 2-sulfatase activity
2. chondroitinsulfatase
3. iduronate sulfatase activity
4. iduronate sulfate sulfatase activity
5. iduronate-2-sulfate sulfatase activity
6. iduronate-2-sulphatase activity
7. iduronide-2-sulfate sulfatase activity
8. idurono-2-sulfatase activity
9. L-iduronate 2-sulfate sulfatase activity
10. L-iduronate-2-sulfate 2-sulfohydrolase activity
11. L-idurono sulfate sulfatase activity
12. L-iduronosulfatase activity
13. sulfo-L-iduronate sulfatase activity
14. sulfoiduronate sulfohydrolase activity
References
1. EC 3.1.6.13
2. MetaCyc 3.1.6.13-RXN
3. Reactome: R-HSA-1678650 "IDS hydrolyses Heparan sulfate chain(5)"
4. Reactome: R-HSA-1793182 "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)"
5. Reactome: R-HSA-2262743 "Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain)"
6. Reactome: R-HSA-9036046 "Defective IDS does not hydrolyse Heparan sulfate chain(5)"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
hydrolase activity is a
hydrolase activity, acting on ester bonds is a
sulfuric ester hydrolase activity is a
iduronate-2-sulfatase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
aspartyl esterase activity is a
carboxylic ester hydrolase activity is a
DNA-3'-diphospho-5'-guanosine diphosphatase is a
enterochelin esterase activity is a
indole-3-acetyl-beta-1-D-glucose hydrolase activity is a
indole-3-acetyl-beta-4-D-glucose hydrolase activity is a
lipase activity is a
phosphoric ester hydrolase activity is a
sulfuric ester hydrolase activity is a
alkyl sulfatase activity is a
arylsulfatase activity is a
cellulose-polysulfatase activity is a
cerebroside-sulfatase activity is a
choline-sulfatase activity is a
chondro-4-sulfatase activity is a
chondro-6-sulfatase activity is a
D-lactate-2-sulfatase activity is a
disulfoglucosamine-6-sulfatase activity is a
endosulfan hemisulfate sulfatase activity is a
endosulfan sulfate hydrolase activity is a
glucuronate-2-sulfatase activity is a
glycosulfatase activity is a
iduronate-2-sulfatase activity is a
monomethyl-sulfatase activity is a
N-acetylgalactosamine-4-sulfatase activity is a
N-acetylgalactosamine-6-sulfatase activity is a
N-acetylglucosamine-6-sulfatase activity is a
N-sulfoglucosamine-3-sulfatase activity is a
steryl-sulfatase activity is a
thiolester hydrolase activity is a
versiconal hemiacetal acetate esterase activity is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a