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Gene ontology
Version 2014-12-22
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Details for N-acetylgalactosamine-4-sulfatase activity
3.1.6.12
Gene ontology ID
GO:0003943
Definition
Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate
Synonyms
1. acetylgalactosamine 4-sulfatase activity
2. arylsulfatase B
3. chondroitinsulfatase
4. N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity
5. N-acetylgalactosamine 4-sulfate sulfohydrolase activity
6. N-acetylgalactosamine-4-sulphatase activity
References
1. EC 3.1.6.12
2. MetaCyc 3.1.6.12-RXN
3. Reactome: R-HSA-1606789 "ARSB hydrolyses DS"
4. Reactome: R-HSA-1793207 "ARSB hydrolyses C4S/C6S chains"
5. Reactome: R-HSA-2282889 "Defective ARSB does not hydrolyse C4S/C6S chains"
6. Reactome: R-HSA-9036065 "Defective ARSB does not hydrolyse DS"
7. Wikipedia: Arylsulfatase B
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