Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+)
1. EC 1.1.1.1452. MetaCyc 1.1.1.145-RXN3. Reactome: R-HSA-192097 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one"
4. Reactome: R-HSA-193789 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one"
5. Reactome: R-HSA-193816 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one"
6. Reactome: R-HSA-196350 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione"
7. Reactome: R-HSA-196372 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol"