1.1.1.153Gene ontology ID
GO:0004757
Definition
Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+
Synonyms
1. 7,8-dihydrobiopterin:NADP+ oxidoreductase activity
References
1. EC 1.1.1.1532. MetaCyc SEPIAPTERIN-REDUCTASE-RXN3. Reactome: R-HSA-1475414 "PTHP is reduced to BH4 by sepiapterin reductase (SPR)"
4. Reactome: R-HSA-1497869 "Salvage - Sepiapterin is reduced to BH2"
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tissue/ enzyme/ localization link to BRENDA