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1.1.1.284Gene ontology ID
GO:0051903
Definition
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+
Synonyms
1. ADH3 activity
2. chi-ADH activity
3. class III alcohol dehydrogenase activity
4. FDH activity
5. formic dehydrogenase activity
6. GD-FALDH activity
7. glutathione-dependent formaldehyde dehydrogenase activity
8. GS-FDH activity
9. NAD- and glutathione-dependent formaldehyde dehydrogenase activity
10. NAD-dependent formaldehyde dehydrogenase activity
11. NAD-linked formaldehyde dehydrogenase activity
12. S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity
References
1. EC 1.1.1.2842. KEGG REACTION: R06983
3. KEGG REACTION: R07140
4. MetaCyc RXN-29625. Reactome: R-HSA-5692237 "ADH5 oxidises S-HMGSH to S-FGSH"
6. RHEA: 19981
7. RHEA: 19985
8. UM-BBD reactionID: r1146
Legend
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is an element of the parent element
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is a part of the parent element
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is related to the parent element
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derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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![](./ontology/inc/tree/images/localization.png)
tissue/ enzyme/ localization link to BRENDA