Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

Id:

restrict to BRENDA links:

Localization

Enzyme

Details for transforming growth factor beta ligand-receptor complex

Gene ontology ID

GO:0070021

Definition

A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand

Synonyms

1. TGF-beta 1:type II receptor:type I receptor complex
2. TGF-beta ligand-receptor complex
3. TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex
4. TGF-beta1 ligand-receptor complex
5. TGF-beta1-beta2 ligand-receptor complex
6. TGF-beta1-type II receptor-type I receptor complex
7. TGF-beta2 ligand-receptor complex
8. TGFb ligand-receptor complex
9. TGFbeta ligand-receptor complex
10. TGFbeta1 ligand-receptor complex
11. TGFbeta1-beta2 ligand-receptor complex
12. TGFbeta2 ligand-receptor complex
13. transforming growth factor beta1-type II receptor-type I receptor complex

References

1. Reactome: R-HSA-170840

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

/

/

at least 1 tissue/ enzyme/ localization link in this branch

/

/

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

cellular_component is a

is a

cellular anatomical entity is a

is a

cell periphery is a

is a

651 BRENDA localization in branch, click for list of all

plasma membrane part of

part of

611 BRENDA localization in branch, click for list of all

plasma membrane protein complex part of

part of

49 BRENDA localization in branch, click for list of all

plasma membrane signaling receptor complex is a

is a

transforming growth factor beta ligand-receptor complex is a

is a

Tree view

Gene ontology

biological_process is a

is a

cellular_component is a

is a

is a

cellular anatomical entity is a

is a

is a

727 BRENDA localization in branch, click for list of all

is a

acrosomal matrix is a

is a

724 BRENDA localization in branch, click for list of all

actin body is a

is a

is a

723 BRENDA localization in branch, click for list of all

actin filament branch point is a

is a

actin filament bundle is a

is a

actin fusion focus is a

is a

actin wave is a

is a

actomyosin is a

is a

717 BRENDA localization in branch, click for list of all

actomyosin contractile ring, distal actin filament layer is a

is a

actomyosin contractile ring, intermediate layer is a

is a

actomyosin contractile ring, proximal layer is a

is a

alae of collagen and cuticulin-based cuticle extracellular matrix is a

is a

annular furrow extracellular matrix is a

is a

annuli extracellular matrix is a

is a

apical complex is a

is a

716 BRENDA localization in branch, click for list of all

apical cytoplasm is a

is a

apical lamina of hyaline layer is a

is a

apical part of cell is a

is a

711 BRENDA localization in branch, click for list of all

apical cortex part of

part of

apical plasma membrane part of

part of

basal body patch part of

part of

Kibra-Ex-Mer complex part of

part of

ascus epiplasm is a

is a

is a

axon collateral is a

is a

709 BRENDA localization in branch, click for list of all

axon hillock is a

is a

708 BRENDA localization in branch, click for list of all

axon initial segment is a

is a

707 BRENDA localization in branch, click for list of all

axonemal basal plate is a

is a

axonemal central apparatus is a

is a

axonemal outer doublet is a

is a

702 BRENDA localization in branch, click for list of all

is a

701 BRENDA localization in branch, click for list of all

bacterial biofilm matrix surface is a

is a

bacterial-type flagellum basal body is a

is a

bacterial-type flagellum filament is a

is a

bacterial-type flagellum hook is a

is a

bacterial-type flagellum hook-filament junction is a

is a

basal labyrinth is a

is a

basal layer of collagen and cuticulin-based cuticle extracellular matrix is a

is a

basal part of cell is a

is a

basolateral cytoplasm is a

is a

bilobe structure is a

is a

blood microparticle is a

is a

Casparian strip is a

is a

is a

696 BRENDA localization in branch, click for list of all

cell division site is a

is a

693 BRENDA localization in branch, click for list of all

cell junction is a

is a

688 BRENDA localization in branch, click for list of all

cell leading edge is a

is a

cell periphery is a

is a

651 BRENDA localization in branch, click for list of all

cell cortex part of

part of

38 BRENDA localization in branch, click for list of all

external encapsulating structure part of

part of

25 BRENDA localization in branch, click for list of all

plasma membrane part of

part of

611 BRENDA localization in branch, click for list of all

133 BRENDA localization in branch, click for list of all

cell trailing edge membrane part of

part of

cellular bud membrane part of

part of

cornified envelope is a

is a

132 BRENDA localization in branch, click for list of all

cytoplasmic side of plasma membrane part of

part of

part of

part of

endomembrane system

130 BRENDA localization in branch, click for list of all

external side of plasma membrane part of

part of

extrinsic component of plasma membrane part of

part of

growth cone membrane part of

part of

immunological synapse part of

part of

62 BRENDA localization in branch, click for list of all

intrinsic component of plasma membrane part of

part of

lateral plasma membrane part of

part of

53 BRENDA localization in branch, click for list of all

part of

52 BRENDA localization in branch, click for list of all

orthogonal array part of

part of

51 BRENDA localization in branch, click for list of all

phagocytic cup part of

part of

50 BRENDA localization in branch, click for list of all

plasma membrane protein complex part of

part of

49 BRENDA localization in branch, click for list of all

1,3-beta-D-glucan synthase complex is a

is a

alpha1-beta1 integrin-alpha3(VI) complex is a

is a

alpha1-beta1 integrin-tissue transglutaminase complex is a

is a

alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex is a

is a

alpha11-beta1 integrin-collagen type I complex is a

is a

alpha2-beta1 integrin-alpha3(VI) complex is a

is a

alpha2-beta1 integrin-CD47 complex is a

is a

alpha2-beta1 integrin-chondroadherin complex is a

is a

alpha3-beta1 integrin-basigin complex is a

is a

alpha3-beta1 integrin-CD151 complex is a

is a

alpha3-beta1 integrin-CD63 complex is a

is a

alpha3-beta1 integrin-thrombospondin complex is a

is a

alpha3-beta1 integrin-tissue transglutaminase complex is a

is a

alpha4-beta1 integrin-CD47 complex is a

is a

alpha4-beta1 integrin-CD53 complex is a

is a

alpha4-beta1 integrin-CD63 complex is a

is a

alpha4-beta1 integrin-CD81 complex is a

is a

alpha4-beta1 integrin-CD82 complex is a

is a

alpha4-beta1 integrin-JAM2 complex is a

is a

alpha4-beta1 integrin-paxillin complex is a

is a

alpha4-beta1 integrin-thrombospondin-1 complex is a

is a

alpha4-beta1 integrin-thrombospondin-2 complex is a

is a

alpha4-beta4 integrin-EMILIN-1 complex is a

is a

alpha5-beta1 integrin-endostatin complex is a

is a

alpha5-beta1 integrin-fibronectin-NOV complex is a

is a

alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex is a

is a

alpha5-beta1 integrin-LPP3 complex is a

is a

alpha5-beta1 integrin-osteopontin complex is a

is a

alpha5-beta1 integrin-tissue transglutaminase complex is a

is a

alpha5-beta5-fibronectin-SFRP2 complex is a

is a

alpha6-beta1 integrin-CD151 complex is a

is a

alpha6-beta1 integrin-CYR61 complex is a

is a

alpha6-beta4 integrin-CD151 complex is a

is a

alpha6-beta4 integrin-CD9 complex is a

is a

alpha6-beta4 integrin-Fyn complex is a

is a

alpha6-beta4 integrin-laminin 5 complex is a

is a

alpha6-beta4 integrin-Shc-Grb2 complex is a

is a

alpha7-beta1 integrin-CD151 complex is a

is a

alpha7-beta1 integrin-focal adhesion kinase complex is a

is a

alpha7-beta1 integrin-laminin alpha-2 complex is a

is a

alpha7-beta1 integrin-nicotinamide riboside kinase complex is a

is a

alpha9-beta1 integrin-ADAM1 complex is a

is a

alpha9-beta1 integrin-ADAM12 complex is a

is a

alpha9-beta1 integrin-ADAM15 complex is a

is a

alpha9-beta1 integrin-ADAM2 complex is a

is a

alpha9-beta1 integrin-ADAM3 complex is a

is a

alpha9-beta1 integrin-ADAM8 complex is a

is a

alpha9-beta1 integrin-ADAM9 complex is a

is a

alpha9-beta1 integrin-osteopontin complex is a

is a

alpha9-beta1 integrin-tenascin complex is a

is a

alpha9-beta1 integrin-thrombospondin-1 complex is a

is a

alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex is a

is a

alpha9-beta1 integrin-VEGF-A complex is a

is a

alpha9-beta1 integrin-VEGF-C complex is a

is a

alpha9-beta1 integrin-VEGF-D complex is a

is a

alphaE-beta7 integrin-E-cadherin complex is a

is a

alphaIIb-beta3 integrin-CD47-FAK complex is a

is a

alphaIIb-beta3 integrin-CD47-Src complex is a

is a

alphaIIb-beta3 integrin-CD9 complex is a

is a

alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex is a

is a

alphaIIb-beta3 integrin-CIB complex is a

is a

alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex is a

is a

alphaIIb-beta3 integrin-ICAM-4 complex is a

is a

alphaIIb-beta3 integrin-talin complex is a

is a

alphaM-beta2 integrin-CD63 complex is a

is a

alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex is a

is a

alphaPDGFR-SHP-2 complex is a

is a

alphav-beta1 integrin-osteopontin complex is a

is a

alphav-beta3 integrin-ADAM15 complex is a

is a

alphav-beta3 integrin-ADAM23 complex is a

is a

alphav-beta3 integrin-CD47 complex is a

is a

alphaV-beta3 integrin-CD47-FCER2 complex is a

is a

alphaV-beta3 integrin-CD98 complex is a

is a

alphav-beta3 integrin-collagen alpha3(VI) complex is a

is a

alphaV-beta3 integrin-EGFR complex is a

is a

alphaV-beta3 integrin-gelsolin complex is a

is a

alphav-beta3 integrin-HMGB1 complex is a

is a

alphav-beta3 integrin-IGF-1-IGF1R complex is a

is a

alphaV-beta3 integrin-laminin alpha-4 complex is a

is a

alphaV-beta3 integrin-LPP3 complex is a

is a

alphaV-beta3 integrin-NOV complex is a

is a

alphav-beta3 integrin-osteopontin complex is a

is a

alphaV-beta3 integrin-paxillin-Pyk2 complex is a

is a

alphav-beta3 integrin-PKCalpha complex is a

is a

alphav-beta3 integrin-thrombospondin complex is a

is a

alphaV-beta3 integrin-tissue transglutaminase complex is a

is a

alphaV-beta3 integrin-tumstatin complex is a

is a

alphav-beta3 integrin-vitronectin complex is a

is a

alphav-beta5 integrin-osteopontin complex is a

is a

alphaV-beta6 integrin-osteopontin complex is a

is a

alphaV-beta6 integrin-TGFbeta-3 complex is a

is a

alphaV-beta8 integrin-MMP14-TGFbeta-1 complex is a

is a

alphaX-beta2 integrin-ICAM-4 complex is a

is a

amino acid transport complex is a

is a

ATP-binding cassette (ABC) transporter complex is a

is a

auxin efflux carrier complex is a

is a

caveolar macromolecular signaling complex is a

is a

CD19-Vav-PIK3R1 complex is a

is a

CFTR-NHERF-ezrin complex is a

is a

ciliary necklace is a

is a

contractile vacuole pore is a

is a

D-amino-acid dehydrogenase complex is a

is a

death-inducing signaling complex is a

is a

3 BRENDA localization in branch, click for list of all

Delta1 complex is a

is a

dystrobrevin complex is a

is a

dystroglycan complex is a

is a

dystrophin-associated glycoprotein complex is a

is a

EGFR-Grb2-Sos complex is a

is a

EGFR-Shc-Grb2-Sos complex is a

is a

Fc receptor complex is a

is a

fibronectin-tissue transglutaminase complex is a

is a

flotillin complex is a

is a

gamma-secretase complex is a

is a

1 BRENDA localization in branch, click for list of all

gamma-secretase-Delta1 complex is a

is a

Grb2-EGFR complex is a

is a

Grb2-Shc complex is a

is a

Grb2-SHP-2 complex is a

is a

Grb2-Sos complex is a

is a

high-affinity iron permease complex is a

is a

inhibin-betaglycan-ActRII complex is a

is a

interleukin-12-interleukin-12 receptor complex is a

is a

interleukin4-interleukin-4 receptor complex is a

is a

low-density lipoprotein receptor complex is a

is a

MdtBC Complex is a

is a

MHC protein complex is a

is a

Ost-alpha/Ost-beta complex is a

is a

plasma membrane fumarate reductase complex is a

is a

plasma membrane proton-transporting ATP synthase complex is a

is a

plasma membrane proton-transporting V-type ATPase complex is a

is a

plasma membrane respiratory chain complex I is a

is a

plasma membrane respiratory chain complex II is a

is a

plasma membrane respiratory chain complex III is a

is a

plasma membrane respiratory chain complex IV is a

is a

plasma membrane signaling receptor complex is a

is a

B cell receptor complex is a

is a

EGFR:ERBB2 complex is a

is a

ERBB3:ERBB2 complex is a

is a

ERBB4-EGFR complex is a

is a

ERBB4-ERBB3 complex is a

is a

ERBB4-ERBB4 complex is a

is a

ERBB4:ERBB2 complex is a

is a

HFE-transferrin receptor complex is a

is a

neurotransmitter receptor complex is a

is a

T cell receptor complex is a

is a

Toll-like receptor 1-Toll-like receptor 2 protein complex is a

is a

Toll-like receptor 2-Toll-like receptor 6 protein complex is a

is a

transforming growth factor beta ligand-receptor complex is a

is a

plasma membrane-derived photosystem I is a

is a

plasma membrane-derived thylakoid photosystem II is a

is a

plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex is a

is a

protocadherin-alpha-protocadherin-gamma complex is a

is a

Shc-EGFR complex is a

is a

Shc-Grb2-Sos complex is a

is a

TAT protein transport complex is a

is a

voltage-gated calcium channel complex is a

is a

Wnt-Frizzled-LRP5/6 complex is a

is a

plasma membrane region part of

part of

plasma membrane respirasome part of

part of

plasma membrane-derived thylakoid lumen part of

part of

part of

3 BRENDA localization in branch, click for list of all

sarcolemma is a

is a

2 BRENDA localization in branch, click for list of all

sperm plasma membrane is a

is a

tetraspanin-enriched microdomain part of

part of

unencapsulated part of cell

cell plate is a

is a

476 BRENDA localization in branch, click for list of all

is a

475 BRENDA localization in branch, click for list of all

cell projection is a

is a

cell septum is a

is a

468 BRENDA localization in branch, click for list of all

cell surface is a

is a

467 BRENDA localization in branch, click for list of all

is a

cell trailing edge is a

is a

cellular bud is a

is a

central element is a

is a

465 BRENDA localization in branch, click for list of all

central plaque of spindle pole body is a

is a

centriolar satellite is a

is a

centrosomal corona is a

is a

is a

464 BRENDA localization in branch, click for list of all

is a

463 BRENDA localization in branch, click for list of all

chromosomal region is a

is a

446 BRENDA localization in branch, click for list of all

is a

compact myelin is a

is a

440 BRENDA localization in branch, click for list of all

concave side of sperm head is a

is a

cone matrix sheath is a

is a

contractile ring is a

is a

439 BRENDA localization in branch, click for list of all

cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a

is a

is a

cytoophidium is a

is a

438 BRENDA localization in branch, click for list of all

is a

437 BRENDA localization in branch, click for list of all

deep fiber is a

is a

dense fibrillar component is a

is a

250 BRENDA localization in branch, click for list of all

dense nuclear body is a

is a

dinoflagellate antapex is a

is a

dinoflagellate apex is a

is a

dinoflagellate epicone is a

is a

dinoflagellate hypocone is a

is a

DNA replication termination region is a

is a

is a

249 BRENDA localization in branch, click for list of all

endonuclear canal is a

is a

248 BRENDA localization in branch, click for list of all

endospore core is a

is a

ensheathing process is a

is a

is a

247 BRENDA localization in branch, click for list of all

epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a

is a

extracellular matrix is a

is a

246 BRENDA localization in branch, click for list of all

extracellular region is a

is a

230 BRENDA localization in branch, click for list of all

extrachromosomal circular DNA is a

is a

212 BRENDA localization in branch, click for list of all

extrachromosomal DNA is a

is a

211 BRENDA localization in branch, click for list of all

extrinsic component of membrane is a

is a

fibrillar center is a

is a

Flemming body is a

is a

gas vesicle shell is a

is a

is a

209 BRENDA localization in branch, click for list of all

granular component is a

is a

208 BRENDA localization in branch, click for list of all

half bridge of spindle pole body is a

is a

host cellular component is a

is a

incipient cellular bud site is a

is a

inclusion body is a

is a

193 BRENDA localization in branch, click for list of all

inner membrane pellicle complex is a

is a

inner plaque of spindle pole body is a

is a

intermediate layer of spindle pole body is a

is a

intracellular immature spore is a

is a

intrinsic component of membrane is a

is a

investment cone is a

is a

lateral element is a

is a

lateral loop is a

is a

lateral part of cell is a

is a

leaflet of membrane bilayer is a

is a

is a

183 BRENDA localization in branch, click for list of all

median body is a

is a

is a

182 BRENDA localization in branch, click for list of all

membrane-enclosed lumen is a

is a

metaphase plate is a

is a

119 BRENDA localization in branch, click for list of all

microtubule bundle is a

is a

microtubule end is a

is a

118 BRENDA localization in branch, click for list of all

microtubule organizing center is a

is a

116 BRENDA localization in branch, click for list of all

is a

107 BRENDA localization in branch, click for list of all

myelin sheath is a

is a

106 BRENDA localization in branch, click for list of all

neck portion of tanycyte is a

is a

is a

105 BRENDA localization in branch, click for list of all

nucleus lagging edge is a

is a

nucleus leading edge is a

is a

oral apparatus is a

is a

103 BRENDA localization in branch, click for list of all

is a

102 BRENDA localization in branch, click for list of all

is a

10 BRENDA localization in branch, click for list of all

periplasmic space is a

is a

9 BRENDA localization in branch, click for list of all

photoreceptor inner segment is a

is a

8 BRENDA localization in branch, click for list of all

polar tube is a

is a

7 BRENDA localization in branch, click for list of all

site of polarized growth is a

is a

6 BRENDA localization in branch, click for list of all

somatodendritic compartment is a

is a

sperm head is a

is a

5 BRENDA localization in branch, click for list of all

sperm head-tail coupling apparatus is a

is a

sporoplasm is a

is a

subapical part of cell is a

is a

supramolecular complex is a

is a

4 BRENDA localization in branch, click for list of all

is a

3 BRENDA localization in branch, click for list of all

tail portion of tanycyte is a

is a

is a

2 BRENDA localization in branch, click for list of all

is a

intracellular is a

is a

81 BRENDA localization in branch, click for list of all

other organism part is a

is a

protein-containing complex is a

is a

55 BRENDA localization in branch, click for list of all

is a

9 BRENDA localization in branch, click for list of all

molecular_function is a

is a

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Release 2023.1 (January 2023)