Details for 3-hydroxyisobutyrate dehydrogenase activity
1.1.1.31Gene ontology ID
GO:0008442
Definition
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+
References
1. EC 1.1.1.312. MetaCyc 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN3. Reactome: R-HSA-508473 "methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+"
4. Reactome: R-HSA-70885 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+"
5. RHEA: 17681
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