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Literature summary extracted from
- Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site (1999), Biochemistry, 38, 11433-11439.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.4.11.10 | not denatured in aliphatic alcohols up to 20% concentration | Vibrio proteolyticus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.10 | 2-propanol | Ki: 8 mM | Vibrio proteolyticus |  |
| 3.4.11.10 | 3-methyl-1-butanol | Ki: 0.98 mM | Vibrio proteolyticus | |
| 3.4.11.10 | benzyl alcohol | Ki: 2.6 mM | Vibrio proteolyticus | |
| 3.4.11.10 | ethanol | Ki: 80 mM | Vibrio proteolyticus | |
| 3.4.11.10 | methanol | Ki: 860 mM | Vibrio proteolyticus | |
| 3.4.11.10 | n-butanol | Ki: 2.7 mM | Vibrio proteolyticus | |
| 3.4.11.10 | n-Propanol | Ki: 11 mM | Vibrio proteolyticus | |
| 3.4.11.10 | phenol | Ki: 4 mM | Vibrio proteolyticus | |
| 3.4.11.10 | tert-butanol | Ki: 10 mM | Vibrio proteolyticus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.10 | Peptides + H2O | Vibrio proteolyticus | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.10 | Vibrio proteolyticus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.10 | Peptides + H2O | - |
Vibrio proteolyticus | ? | - |
? | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.11.10 | 0.98 | - |
3-methyl-1-butanol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 2.6 | - |
benzyl alcohol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 2.7 | - |
n-butanol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 4 | - |
phenol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 8 | - |
2-propanol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 10 | - |
tert-butanol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 11 | - |
n-Propanol | - |
Vibrio proteolyticus | |
| 3.4.11.10 | 80 | - |
ethanol | - |
Vibrio proteolyticus | |
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Release 2023.1 (January 2023)
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