EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.1 | acetazolamide | - |
Leptonychotes weddellii | |
4.2.1.1 | azide | - |
Leptonychotes weddellii | |
4.2.1.1 | benzolamide | - |
Leptonychotes weddellii | |
4.2.1.1 | bicarbonate | high inhibition | Leptonychotes weddellii | |
4.2.1.1 | brinzolamide | - |
Leptonychotes weddellii | |
4.2.1.1 | bromide | - |
Leptonychotes weddellii | |
4.2.1.1 | Carbonate | high inhibition | Leptonychotes weddellii | |
4.2.1.1 | chloride | - |
Leptonychotes weddellii | |
4.2.1.1 | Cyanate | high inhibition | Leptonychotes weddellii | |
4.2.1.1 | cyanide | high inhibition | Leptonychotes weddellii | |
4.2.1.1 | dichlorophenamide | - |
Leptonychotes weddellii | |
4.2.1.1 | dorzolamide | - |
Leptonychotes weddellii | |
4.2.1.1 | fluoride | - |
Leptonychotes weddellii | |
4.2.1.1 | H2NSO2NH2 | - |
Leptonychotes weddellii | |
4.2.1.1 | H2NSO3H | - |
Leptonychotes weddellii | |
4.2.1.1 | HSO3- | - |
Leptonychotes weddellii | |
4.2.1.1 | hydrochlorothiazide | - |
Leptonychotes weddellii | |
4.2.1.1 | Iodide | - |
Leptonychotes weddellii | |
4.2.1.1 | methazolamide | - |
Leptonychotes weddellii | |
4.2.1.1 | additional information | no inhibition by perchlorate | Leptonychotes weddellii | |
4.2.1.1 | nitrate | - |
Leptonychotes weddellii | |
4.2.1.1 | nitrite | - |
Leptonychotes weddellii | |
4.2.1.1 | PhAsO3H2 | - |
Leptonychotes weddellii | |
4.2.1.1 | PhB(OH)2 | - |
Leptonychotes weddellii | |
4.2.1.1 | saccharin | - |
Leptonychotes weddellii | |
4.2.1.1 | sulfamate | - |
Leptonychotes weddellii | |
4.2.1.1 | sulfamide | high inhibition | Leptonychotes weddellii | |
4.2.1.1 | sulfate | - |
Leptonychotes weddellii | |
4.2.1.1 | Sulfide | - |
Leptonychotes weddellii | |
4.2.1.1 | thiocyanate | high inhibition | Leptonychotes weddellii | |
4.2.1.1 | zonisamide | - |
Leptonychotes weddellii |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.1 | Zn2+ | catalytically crucial | Leptonychotes weddellii |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.2.1.1 | 30000 | - |
x * 30000, about, SDS-PAGE | Leptonychotes weddellii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.1 | H2CO3 | Leptonychotes weddellii | - |
CO2 + H2O | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.1 | Leptonychotes weddellii | - |
adult female Weddell seals | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.2.1.1 | heart | - |
Leptonychotes weddellii | - |
4.2.1.1 | intestine | - |
Leptonychotes weddellii | - |
4.2.1.1 | kidney | - |
Leptonychotes weddellii | - |
4.2.1.1 | liver | - |
Leptonychotes weddellii | - |
4.2.1.1 | lung | - |
Leptonychotes weddellii | - |
4.2.1.1 | spleen | - |
Leptonychotes weddellii | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.1 | H2CO3 | - |
Leptonychotes weddellii | CO2 + H2O | - |
r |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.2.1.1 | ? | x * 30000, about, SDS-PAGE | Leptonychotes weddellii |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.1 | alpha-carbonic anhydrase | - |
Leptonychotes weddellii |
4.2.1.1 | lwCA | - |
Leptonychotes weddellii |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
4.2.1.1 | 20 | - |
assay at | Leptonychotes weddellii |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.1.1 | 7.5 | - |
assay at | Leptonychotes weddellii |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
4.2.1.1 | 0.046 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | PhB(OH)2 | |
4.2.1.1 | 0.055 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | H2NSO3H | |
4.2.1.1 | 0.057 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | PhAsO3H2 | |
4.2.1.1 | 0.06 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Carbonate | |
4.2.1.1 | 0.07 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | cyanide | |
4.2.1.1 | 0.07 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | H2NSO2NH2 | |
4.2.1.1 | 0.087 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Cyanate | |
4.2.1.1 | 0.097 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | thiocyanate | |
4.2.1.1 | 0.1 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | bicarbonate | |
4.2.1.1 | 0.59 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | HSO3- | |
4.2.1.1 | 0.74 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | fluoride | |
4.2.1.1 | 0.82 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | sulfate | |
4.2.1.1 | 0.83 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | azide | |
4.2.1.1 | 0.89 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | chloride | |
4.2.1.1 | 0.9 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | nitrite | |
4.2.1.1 | 1 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Sulfide | |
4.2.1.1 | 1.01 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | bromide | |
4.2.1.1 | 20 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | Iodide | |
4.2.1.1 | 55.6 | - |
pH 7.5, 20°C, inhibition of CO2 hydration activity | Leptonychotes weddellii | nitrate |