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Literature summary extracted from

  • Santos-Silva, T.; Ferroni, F.; Thapper, A.; Marangon, J.; Gonzalez, P.J.; Rizzi, A.C.; Moura, I.; Moura, J.J.; Romao, M.J.; Brondino, C.D.
    Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system (2009), J. Am. Chem. Soc., 131, 7990-7998.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.2.99.7 sitting drop vapor diffusion method, using 30% (v/v) 2-propanol, 0.2 M magnesium chloride, and 0.2 M HEPES buffer (pH 7.6) Megalodesulfovibrio gigas

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.99.7 arsenite irreversible inhibitor, complete inhibition at 0.024 mM Megalodesulfovibrio gigas
1.2.99.7 cyanide competitive reversible inhibitor, 30.9% inhibition at 50 mM Megalodesulfovibrio gigas
1.2.99.7 ethylene glycol mixed-type reversible inhibitor, 21.9% inhibition at 1 mM Megalodesulfovibrio gigas
1.2.99.7 glycerol competitive reversible inhibitor, 52% inhibition at 1 mM Megalodesulfovibrio gigas

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.99.7 0.0097
-
 benzaldehyde in 50 mM Tris-HCl buffer (pH 7.6), at 37°C Megalodesulfovibrio gigas

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.99.7 Molybdenum contains molybdenum Megalodesulfovibrio gigas

Organism

EC Number Organism UniProt Comment Textmining
1.2.99.7 Megalodesulfovibrio gigas Q46509
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.99.7
-
 Megalodesulfovibrio gigas

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.99.7 benzaldehyde + H2O + 2,6-dichlorophenolindophenol
-
 Megalodesulfovibrio gigas benzoate + reduced 2,6-dichlorophenol-indophenol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.99.7 aldehyde oxidoreductase
-
 Megalodesulfovibrio gigas
1.2.99.7 AOR
-
 Megalodesulfovibrio gigas

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.2.99.7 1.12
-
 benzaldehyde in 50 mM Tris-HCl buffer (pH 7.6), at 37°C Megalodesulfovibrio gigas