EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.15.1 | captopril | microarray gene expression profiling of the aorta during atherosclerosis prevention with the ACE inhibitor, overview. Captopril treatment for 7 months strongly decreases the recruitment of proatherogenic immune cells into the aorta. Captopril-mediated inhibition of plaque infiltrating immune cells involves downregulation of the C-C chemokine receptor 9, CCR9, phenotype and physiological mechanism, overview | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.15.1 | angiotensin I + H2O | Mus musculus | - |
angiotensin II + His-Leu | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.15.1 | Mus musculus | - |
atherosclerosis-prone apolipoprotein E-deficient C57BL/6J mice | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.15.1 | aorta | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.15.1 | angiotensin I + H2O | - |
Mus musculus | angiotensin II + His-Leu | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.15.1 | ACE | - |
Mus musculus |
3.4.15.1 | angiotensin-converting enzyme | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.15.1 | malfunction | atherosclerosis-enhancing effects of angiotensin II | Mus musculus |