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Literature summary extracted from

  • Lassen, N.; Bateman, J.B.; Estey, T.; Kuszak, J.R.; Nees, D.W.; Piatigorsky, J.; Duester, G.; Day, B.J.; Huang, J.; Hines, L.M.; Vasiliou, V.
    Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice (2007), J. Biol. Chem., 282, 25668-25676.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.4 51000
-
 SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.4 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.4 cornea
-
 Mus musculus
-
1.2.1.4 additional information undetectable in the lens Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.4 0.853
-
 wild type enzyme from cornea, using propionaldehyde and NAD+ as substrates Mus musculus
1.2.1.4 3.43
-
 wild type enzyme from cornea, using NADP+ and benzaldehyde as substrates Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.4 4-hydroxy-2-nonenal + NADP+
-
 Mus musculus (2E)-4-hydroxynon-2-enoate + NADPH + H+
-
 ?
1.2.1.4 benzaldehyde + NADP+
-
 Mus musculus benzoate + NADPH + H+
-
 ?
1.2.1.4 malondialdehyde + NADP+ poor substrate Mus musculus ?
-
 ?
1.2.1.4 propionaldehyde + NADP+ poor substrate Mus musculus propionate + NADPH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.4 aldehyde dehydrogenase 3A1
-
 Mus musculus
1.2.1.4 ALDH3A1
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.4 NADP+
-
 Mus musculus