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Literature summary extracted from
- Molecular cloning and characterization of the gene encoding squalene epoxidase in Panax notoginseng (2008), DNA Seq., 19, 270-273.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.14.17 | DNA and amino acid sequence determination and analysis, quantitative expression analysis, phylogenetic tree | Panax notoginseng |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.14.17 | membrane | membrane-associated enzyme | Panax notoginseng | 16020 | - |
| 1.14.14.17 | microsome | membrane-associated enzyme | Panax notoginseng | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.14.17 | 59140 | - |
x * 59140, sequence calculation | Panax notoginseng |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.17 | squalene + AH2 + O2 | Panax notoginseng | rate-limiting enzyme in the triterpene saponins biosynthetic pathway, overview | (S)-squalene-2,3-epoxide + A + H2O | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.17 | Panax notoginseng | Q1PID4 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.17 | additional information | quantitative expression analysis | Panax notoginseng | - |
| 1.14.14.17 | root | high expression level in roots, especially in 3-year-old roots | Panax notoginseng | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.17 | squalene + AH2 + O2 | - |
Panax notoginseng | (S)-squalene-2,3-epoxide + A + H2O | - |
? | |
| 1.14.14.17 | squalene + AH2 + O2 | rate-limiting enzyme in the triterpene saponins biosynthetic pathway, overview | Panax notoginseng | (S)-squalene-2,3-epoxide + A + H2O | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.14.14.17 | ? | x * 59140, sequence calculation | Panax notoginseng |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.17 | squalene epoxidase | - |
Panax notoginseng |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.17 | FAD | - |
Panax notoginseng | |
| 1.14.14.17 | additional information | the enzyme sequence contains a Rossmann-dinucleotide binding fold and NAD(P)-binding site | Panax notoginseng |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 1.14.14.17 | Panax notoginseng | sequence calculation | - |
8.81 |
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