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Literature summary extracted from

  • Kim, J.Y.; Kim, J.K.; Lee, S.O.; Kim, C.K.; Lee, K.
    Multicomponent phenol hydroxylase-catalysed formation of hydroxyindoles and dyestuffs from indole and its derivatives (2005), Lett. Appl. Microbiol., 41, 163-168.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.14.13.7 synthesis the multicomponent phenol hydroxylases can be used as biocatalysts for producing dyes, e.g. indigo, and hydroxyindoles such as 7-hydroxyindole from indole and its derivatives, overview, multicomponent phenol hydroxylases may serve as potential agents for organic syntheses as well as bioremediation Pseudomonas sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.7 expression of enzyme from strain KL33 and KL28 in Escherichia coli Pseudomonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.7 additional information Pseudomonas sp. phenol degradation pathway, overview ?
-
 ?
1.14.13.7 phenol + NADPH + O2 Pseudomonas sp.
-
 catechol + NADP+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.7 Pseudomonas sp.
-
 strains KL28 and KL33
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.7 additional information strain KL28 is a strain that can grow on n-alkylphenols as a carbon and energy source Pseudomonas sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.7 2-methylindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 3-cyanoindole + NADPH + O2 substrate only of strain KL28 Pseudomonas sp. ?
-
 ?
1.14.13.7 4-hydroxyindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 4-methoxyindole + NADPH + O2 substrate only of strain KL28 Pseudomonas sp. ?
-
 ?
1.14.13.7 4-methylindole + NADPH + O2 substrate only of strain KL28 Pseudomonas sp. ?
-
 ?
1.14.13.7 5-aminoindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 5-fluoroindole + NADPH + O2 substrate only of strain KL33 Pseudomonas sp. ?
-
 ?
1.14.13.7 5-hydroxyindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 5-methoxyindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 5-methylindole + NADPH + O2 substrate only of strain KL33 Pseudomonas sp. ?
-
 ?
1.14.13.7 6-chloroindole + NADPH + O2 substrate only of strain KL33 Pseudomonas sp. ?
-
 ?
1.14.13.7 6-methoxyindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 6-methylindole + NADPH + O2 substrate only of strain KL33 Pseudomonas sp. ?
-
 ?
1.14.13.7 7-chloroindole + NADPH + O2 substrate only of strain KL33 Pseudomonas sp. ?
-
 ?
1.14.13.7 7-methylindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 indole + NADPH + O2
-
 Pseudomonas sp. 7-hydroxyindole + NADP+ + H2O
-
 ?
1.14.13.7 additional information phenol degradation pathway, overview Pseudomonas sp. ?
-
 ?
1.14.13.7 additional information the enzyme is a multicomponent phenol hydroxylase, production of dyes from indole derivatives by recombinant enzymes expressed in Escherichia coli, substrate specificities of the enzyme from strain KL28 and KL33, the products formed by the enzyme from the two strain are different, detailed overview Pseudomonas sp. ?
-
 ?
1.14.13.7 oxindole + NADPH + O2
-
 Pseudomonas sp. ?
-
 ?
1.14.13.7 phenol + NADPH + O2
-
 Pseudomonas sp. catechol + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.7 multicomponent phenol hydroxylase
-
 Pseudomonas sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.7 NADPH
-
 Pseudomonas sp.