Literature summary extracted from

Nunez, S.; Wing, C.; Antoniou, D.; Schramm, V.L.; Schwartz, S.D.
Insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase (2006), J. Phys. Chem. A, 110, 463-472.

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.4.2.1	F159G	mutant displays a strong increase in KM and modest decrease in kcat	Homo sapiens
2.4.2.1	F200G	mutant displays a strong increase in KM and modest decrease in kcat	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.4.2.1	immucillin-H	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.1	Homo sapiens	P00491	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.1	guanosine + phosphate	insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase	Homo sapiens	guanine + alpha-D-ribose 1-phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.1	hPNP	-	Homo sapiens

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Release 2023.1 (January 2023)